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Email

jvince@unimelb.edu.au

Credentials


Position
Honorary (Principal Fellow)
Department of Medical Biology (WEHI)
Education
PhD
University of Melbourne

A/Prof James Vince

Honorary (Principal Fellow)
Department of Medical Biology (WEHI)

106 Scholarly works
1 Projects

HIGHLIGHTS

  • 2026

    Journal article

    The PANoptosis hypothesis examined.
    DOI: 10.1038/s41580-026-00970-4
  • 2026

    Journal article

    IAP-based biodegraders can convert necroptosis to apoptosis and eliminate cancer driving protein complexes
    DOI: 10.1016/j.chembiol.2026.03.005
  • 2026

    Journal article

    Inhibition of the NLRP3 Inflammasome With MCC950 Improves Gut Health in Huntington's Disease Mice
    DOI: 10.1111/jnc.70419
  • 2026

    Journal article

    Author Correction: A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation (EMBO reports, (2023), 24, 11, (e56865), 10.15252/embr.202356865)
    DOI: 10.1038/s44319-025-00609-z
  • 2026

    Journal article

    Correction: NEDD4L-mediated Gasdermin D and E ubiquitination regulates cell death and tissue injury (Cell Death & Differentiation, (2025), 10.1038/s41418-025-01598-1)
    DOI: 10.1038/s41418-025-01653-x
  • 2023

    Research Grant

    Validating a Unique Anti-Inflammatory Therapy to Treat Heart Failure After a Heart Attack in Type 2 Diabetic Patients With Co-Morbid Hypertension
  • 2014

    Journal article

    RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
    DOI: 10.1016/j.cell.2014.04.019
James Vince

RECENT SCHOLARLY WORKS

  • 2025

    Journal article

    Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection
    DOI: 10.1038/s41467-025-65098-z
  • 2025

    Journal article

    Targeting the NLRP3 Inflammasome-Gasdermin D Axis to Combat Cardiovascular Diseases
    DOI: 10.1016/j.yjmcc.2025.09.006
  • 2025

    Journal article

    Necroptotic cell death consequences and disease relevance
    DOI: 10.1038/s41590-025-02298-1
  • 2025

    Journal article

    Lipid nanoparticle-delivered intrabodies for inhibiting necroptosis and pyroptosis
    DOI: 10.1042/bcj20253191
  • 2025

    Journal article

    NLRP3 inflammasome–driven hemophagocytic lymphohistiocytosis occurs independent of IL-1β and IL-18 and is targetable by BET inhibitors
    DOI: 10.1126/sciadv.adv0079

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