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Email

majewskii@unimelb.edu.au

Credentials


Position
Honorary (Principal Fellow)
Department of Medical Biology (WEHI)
Education
PhD
University of Melbourne

A/Prof Ian Majewski

Honorary (Principal Fellow)
Department of Medical Biology (WEHI)

58 Scholarly works
0 Projects

HIGHLIGHTS

  • 2022

    Journal article

    Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy
    DOI: 10.1182/blood.2022016040
  • 2021

    Journal article

    Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias
    DOI: 10.1182/blood.2020010167
  • 2020

    Journal article

    Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT): A Phase Ib Dose-Escalation Study of Venetoclax Combined with Modified Intensive Chemotherapy
    DOI: 10.1200/JCO.20.00572
  • 2020

    Journal article

    Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML
    DOI: 10.1182/BLOOD.2019003988
  • 2019

    Journal article

    Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations
    DOI: 10.1038/s41467-019-10363-1
  • 2019

    Journal article

    Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia
    DOI: 10.1158/2159-8290.CD-18-1119
  • 2018

    Journal article

    MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML
    DOI: 10.1182/blood-2018-05-852566
Ian Majewski

RECENT SCHOLARLY WORKS

  • 2026

    Journal article

    Mbd4 and MutSα protect cells from spontaneous deamination of 5-methylcytosine
    DOI: 10.1093/nar/gkaf1493
  • 2023

    Journal article

    Uridine-cytidine kinase 2 potentiates the mutagenic influence of the antiviral β-d-N4-hydroxycytidine
    DOI: 10.1093/nar/gkad1002
  • 2023

    Journal article

    Overexpression of Lmo2 initiates T-lymphoblastic leukemia via impaired thymocyte competition
    DOI: 10.1084/jem.20212383
  • 2022

    Journal article

    Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies
    DOI: 10.1186/s13073-022-01131-w
  • 2022

    Journal article

    ALLSorts: an RNA-Seq subtype classifier for B-cell acute lymphoblastic leukemia
    DOI: 10.1182/bloodadvances.2021005894
  • 2022

    Journal article

    Germline MBD4 deficiency causes a multi-tumor predisposition syndrome
    DOI: 10.1016/j.ajhg.2022.03.018
  • 2021

    Journal article

    MINTIE: identifying novel structural and splice variants in transcriptomes using RNA-seq data
    DOI: 10.1186/s13059-021-02507-8
  • 2021

    Journal article

    Comprehensive characterization of single-cell full-length isoforms in human and mouse with long-read sequencing
    DOI: 10.1186/s13059-021-02525-6

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