Dr Laura Jacobson
Honorary (Principal Fellow)
Department of Biochemistry and Pharmacology
102 Scholarly works
3 Projects
HIGHLIGHTS
2026
Journal article
PS19 mouse tauopathy is associated with sex-dependent sleep loss and hyperarousal, and predicts cognitive performance
DOI: 10.1016/j.neurobiolaging.2025.12.0012026
Journal article
Locus coeruleus inhibition in tau transgenic mice to treat neuropsychiatric and sleep disturbances in Alzheimer’s disease
DOI: 10.1016/j.sleep.2025.1075972026
Journal article
Orexin receptor antagonism rescues sleep and improves anxiety in tau-transgenic mice, but only improves cognition sex-dependently
DOI: 10.1016/j.sleep.2025.1069232026
Journal article
Characterization of locus coeruleus neuronal properties with aging in two mouse models of tauopathy
DOI: 10.1177/138728772513935152026
Journal article
Waking up to the evidence of pharmacological treatments used to manage sleep disorders in people with dementia and mild cognitive impairment—A scoping review
DOI: 10.1016/j.pharmr.2025.1000942025
Journal article
The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors
DOI: 10.1111/bph.702302023
Research Grant
Orexinergic Mechanisms in Alzheimer's Disease
RECENT SCHOLARLY WORKS
2025
Journal article
Rapid eye movement sleep: Who needs it? Creativity mechanisms and psychiatric applications of REM sleep enhancement
DOI: 10.1177/026988112513651792025
Conference Proceedings
32. Orexin 1 Receptor Antagonism Exacerbates Sleep Deficits and Reduces Anxiety in a Tau Transgenic Mouse Model of Alzheimer's Disease
DOI: 10.1016/j.jagp.2025.04.0342025
Journal article
Investigating the effects of orexin receptor 1 antagonism on decision making under uncertainty
DOI: 10.1016/j.bbr.2025.1156912025
Journal article
Orexin receptors in GtoPdb v.2025.3
DOI: 10.2218/gtopdb/f51/2025.3
RECENT PROJECTS
2016
Research Grant
Determining the Contribution of Orexin Receptor Subtypes to Sleep Architecture
2016
Research Grant
Determining the Contribution of Orexin Receptor Subtypes to Sleep Architecture