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Email

alistair.chalk@unimelb.edu.au

Credentials


Position
Honorary Fellow
Faculty of Medicine, Dentistry and Health Sciences - Admin
ORCID

0000-0002-9630-6236

Alistair Chalk

Honorary Fellow
Faculty of Medicine, Dentistry and Health Sciences

65 Scholarly works
0 Projects

HIGHLIGHTS

  • 2026

    Journal article

    Minute amounts of helicase-deficient truncated RECQL4 are sufficient for DNA replication
    DOI: 10.1038/s44319-026-00727-2
  • 2026

    Journal article

    KLHDC3 deficiency in mice reveals essential roles in development, survival, and adiposity via the DesCEND ubiquitin pathway
    DOI: 10.1186/s12864-026-12574-5
  • 2025

    Journal article

    AMPK phosphosite profiling by label-free mass spectrometry reveals a multitude of mTORC1-regulated substrates
    DOI: 10.1038/s44324-025-00052-7
  • 2024

    Journal article

    GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing
    DOI: 10.1126/sciimmunol.adk0412
  • 2024

    Journal article

    3192 – ADAR1P150 PROTEIN, INDEPENDENT OF ITS A-TO-I RNA EDITING ACTIVITY, REGULATES PERIPHERAL T CELL HOMEOSTASIS AND HSC REPOPULATING CAPACITY
    DOI: 10.1016/j.exphem.2024.104512
  • 2023

    Journal article

    Over-expression of ADAR1 in mice does not initiate or accelerate cancer formation in vivo
    DOI: 10.1093/narcan/zcad023
  • 2023

    Journal article

    The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant
    DOI: 10.15252/embr.202255835
Alistair Chalk

RECENT SCHOLARLY WORKS

  • 2023

    Journal article

    3210 – OVER-EXPRESSION OF ADAR1 IN MICE DOES NOT INITIATE OR ACCELERATE CANCER FORMATION IN VIVO.
    DOI: 10.1016/j.exphem.2023.06.317
  • 2022

    Journal article

    Srsf2P95H/ co-operates with loss of TET2 to promote myeloid bias and initiate a chronic myelomonocytic leukemia-like disease in mice
    DOI: 10.1038/s41375-022-01727-6
  • 2022

    Journal article

    Genome-wide screening identifies cell-cycle control as a synthetic lethal pathway with SRSF2P95H mutation
    DOI: 10.1182/bloodadvances.2021004571

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