Dr. Craig Morton
Senior Research Fellow
Biochemistry and Pharmacology
110 Scholarly works
2 Projects
HIGHLIGHTS
2021
Journal article
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome.
DOI: 10.1073/pnas.21072131182021
Journal article
Functional and structural analysis of cytokine-selective IL6ST defects that cause recessive hyper-IgE syndrome
DOI: 10.1016/j.jaci.2021.02.0442021
Book Chapter
X-ray crystallography shines a light on pore-forming toxins.
DOI: 10.1016/bs.mie.2021.01.0012020
Journal article
A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins
DOI: 10.1128/mBio.02351-202020
Research Grant
PORE-FORMING TOXINS: MORE THAN ONE WAY TO MAKE A HOLE
2019
Journal article
The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis
DOI: 10.1038/s41564-019-0524-42018
Research Contracts
SECONDMENT - SAL CONTRIBUTION - CRAIG MORTON - 18/18 - ST VINCENTS INS OF MED RESEARCH
RECENT SCHOLARLY WORKS
2020
Journal article
The structure of the extracellular domains of human interleukin 11? receptor reveals mechanisms of cytokine engagement
DOI: 10.1074/jbc.RA119.0123512020
Journal article
The Crystal Structure of the Manganese Superoxide Dismutase from Geobacillus stearothermophilus: Parker and Blake (1988) Revisited
DOI: 10.1071/CH193462019
Journal article
Bridging Crystal Engineering and Drug Discovery by Utilizing Intermolecular Interactions and Molecular Shapes in Crystals
DOI: 10.1002/ange.2019066022019
Conference Proceedings
CRYO-EM OF THE MALARIA PARASITE PA28/20S PROTEASOME COMPLEX REVEALS AN UNUSUAL ACTIVATION MECHANISM WITH IMPLICATIONS FOR ARTEMISININ SENSITIVITY
2019
Journal article
Bridging Crystal Engineering and Drug Discovery by Utilizing Intermolecular Interactions and Molecular Shapes in Crystals
DOI: 10.1002/anie.201906602