A/Prof Lev Kats
Honorary Conjoint Principal Fellow
The Sir Peter MacCallum Department of Oncology
24 Scholarly works
3 Projects
HIGHLIGHTS
2026
Journal article
Discovery and Characterization of VPRBP/DCAF1 Kinase Inhibitor Analogs as Microtubular Destabilizing Agents with Potent Antimyeloma Activity
DOI: 10.1158/1535-7163.MCT-25-03062026
Journal article
Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia
DOI: 10.1016/j.cell.2025.10.0282025
Journal article
Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
DOI: 10.1038/s41467-025-59021-92024
Journal article
FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
DOI: 10.1038/s41586-024-07242-12023
Journal article
The curious case of IDH mutant acute myeloid leukaemia: biochemistry and therapeutic approaches
DOI: 10.1042/BST202300172023
Research grants (ARC, NHMRC, MRFF)
Understanding and Targeting Self-Renewal in Aggressive Blood Cancers
2022
Journal article
Non-genetic determinants of malignant clonal fitness at single-cell resolution
DOI: 10.1038/s41586-021-04206-7
RECENT SCHOLARLY WORKS
2023
Journal article
Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma
DOI: 10.1073/pnas.23064141202022
Journal article
Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells
DOI: 10.1016/j.celrep.2022.1111822022
Journal article
Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma
DOI: 10.1038/s41375-022-01571-82021
Journal article
CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy
DOI: 10.1038/s41467-021-23331-5
RECENT PROJECTS
2016
Research Grant
Understanding Response and Resistance to Inhibition of Mutant Isocitrate Dehydrogenase in Acute Myeloid Leukaemia
2014
Research Grant
Exploring the Role of the Tumour Suppressor PML in Maintenance Of Leukaemia Initiating Cells