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Email

seymourj@unimelb.edu.au

Credentials


Position
Honorary (Professorial Fellow)
Department of Medicine
ORCID

0000-0003-2188-6835

Prof John Seymour

Honorary (Professorial Fellow)
Department of Medicine

1153 Scholarly works
9 Projects

HIGHLIGHTS

  • 2023

    Research grants (ARC, NHMRC, MRFF)

    PRECISION\2013 Pharmacogenomic Medicines Optimisation for People With Cancer
  • 2022

    Journal article

    Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy
    DOI: 10.1182/blood.2022016040
  • 2022

    Journal article

    Enrichment of BTK Leu528Trp mutations in patients with CLL on zanubrutinib: potential for pirtobrutinib cross-resistance
    DOI: 10.1182/bloodadvances.2022008325
  • 2022

    Journal article

    Clonal hematopoiesis, myeloid disorders and BAX-mutated myelopoiesis in patients receiving venetoclax for CLL
    DOI: 10.1182/blood.2021012775
  • 2021

    Journal article

    Outcomes of patients with CLL sequentially resistant to both BCL2 and BTK inhibition
    DOI: 10.1182/bloodadvances.2021005083
  • 2021

    Journal article

    Efficacy of venetoclax plus rituximab for relapsed CLL: 5-year follow-up of continuous or limited- duration therapy
    DOI: 10.1182/blood.2020009578
  • 2020

    Research grants (other domestic)

    Exercise Oncology Services Closer to Home: Improving Equity of Access and Survivor Outcome S Through the Development of a Multi-Disciplinary Digitally-Delivered Service.
John Seymour

RECENT SCHOLARLY WORKS

  • 2026

    Journal article

    ROCKET-CLL: A randomized, open-label, multicenter, phase 3 study of rocbrutinib (LP-168) versus pirtobrutinib in covalent BTK inhibitor (cBTKi) in pretreated relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL).
    DOI: 10.1200/jco.2026.44.16_suppl.tps7100
  • 2026

    Journal article

    Marginal Zone Lymphoma: 2026 Update on Diagnosis and Management
    DOI: 10.1002/ajh.70289
  • 2026

    Journal article

    Obinutuzumab, lenalidomide, and venetoclax for the initial treatment of patients with advanced-stage follicular lymphoma: Results of the Phase Ib/II LEVERAGE study
    DOI: 10.1002/hem3.70386
  • 2026

    Journal article

    Venetoclax retreatment in chronic lymphocytic leukemia is biologically rational and clinically effective
    DOI: 10.1182/bloodadvances.2026019871
  • 2026

    Journal article

    Safety and activity of pirtobrutinib in patients with relapsed or refractory Waldenström macroglobulinaemia: 5-year follow-up of the open-label, multicentre, phase 1/2 BRUIN trial
    DOI: 10.1016/S2352-3026(26)00037-2
  • 2026

    Journal article

    Secondary outcomes of the TROG 99.03 randomized trial of systemic therapy after involved-field radiotherapy in early-stage follicular lymphoma, including toxicity, relapse and second malignancy data
    DOI: 10.1016/j.radonc.2026.111388
  • 2026

    Journal article

    The landscape and evolution of clonal hematopoiesis in chronic lymphocytic leukemia
    DOI: 10.1182/blood.2025029905
  • 2026

    Journal article

    Venetoclax and ibrutinib induces durable clinical responses in marginal zone lymphoma
    DOI: 10.1182/bloodadvances.2025016646

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