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Email

mroy1@unimelb.edu.au

Credentials


Position
Honorary (Fellow)
Department of Medical Biology (WEHI)

Mr Michael Roy

Honorary (Fellow)
Department of Medical Biology (WEHI)

17 Scholarly works
0 Projects

HIGHLIGHTS

  • 2026

    Journal article

    Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors
    DOI: 10.1038/s42004-025-01871-x
  • 2025

    Journal article

    Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexes
    DOI: 10.1038/s41467-025-63713-7
  • 2025

    Journal article

    Accurate PROTAC-targeted degradation prediction with DegradeMaster
    DOI: 10.1093/bioinformatics/btaf191
  • 2024

    Journal article

    Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids
    DOI: 10.1111/febs.17031
  • 2023

    Journal article

    Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling
    DOI: 10.1038/s41467-023-38869-9
  • 2022

    Journal article

    A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
    DOI: 10.1038/s41467-022-33430-6
  • 2022

    Journal article

    Distinct PEAK3 interactors and outputs expand the signaling potential of the PEAK pseudokinase family
    DOI: 10.1126/scisignal.abj3554
Michael Roy

RECENT SCHOLARLY WORKS

  • 2022

    Book Chapter

    Production and purification of the PEAK pseudokinases for structural and functional studies
    DOI: 10.1016/bs.mie.2022.03.022
  • 2021

    Journal article

    Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1
    DOI: 10.1038/s42003-021-02631-y
  • 2021

    Journal article

    The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs
    DOI: 10.1042/BCJ20210572

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