A/Prof Paul Beavis
Honorary Conjoint Professorial Fellow
The Sir Peter MacCallum Department of Oncology
107 Scholarly works
27 Projects
HIGHLIGHTS
2026
Journal article
High efficiency CRISPR knock-in demonstrates that TCF1 is insufficient to reverse T cell exhaustion
DOI: 10.1038/s41467-026-69671-y2026
Journal article
The genome takes the wheel: CAR T with built-in circuits
DOI: 10.1016/j.iotech.2026.1015972026
Research grants (international)
Using Novel Biological Therapies to Target a Tumor-Specific Isoform of HER2 for the Treatment of Advanced Breast Cancer.
2026
Journal article
Development of a high-affinity anti-ROR1 variable region for broad anti-cancer immunotherapy
DOI: 10.1016/j.ymthe.2025.11.0212026
Journal article
Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8 T cells in lymph nodes
DOI: 10.1038/s41590-026-02419-42026
Research grants (ARC, NHMRC, MRFF)
Gene Engineering Approaches to Enhance the Efficacy of Adoptive Cellular Therapy of Cancer
2024
Research grants (international)
Enhancing the Efficacy of Adoptive Cellular Therapy Through Advanced Genome Engineering
RECENT SCHOLARLY WORKS
2026
Journal article
Implantable drug delivery system improves tolerability of anti-CD40/anti-PD1 and chemotherapy in a murine model of breast cancer
DOI: 10.1016/j.ejps.2025.1073592026
Journal article
CDK4/6 inhibition enhances CAR-T cell therapy in solid tumors
DOI: 10.1016/j.ymthe.2026.03.0242025
Journal article
Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
DOI: 10.1038/s41467-025-59021-92025
Journal article
Microbiota-derived butyrate promotes a FOXO1-induced stemness program and preserves CD8 T cell immunity against melanoma
DOI: 10.1016/j.immuni.2025.10.0042025
Conference Proceedings
Development of a novel CAR-T cell therapy using a multimodal approach to target T cell lymphoma
DOI: 10.1182/blood-2025-41122025
Conference Proceedings
297 Identifying optimal tumour-specific genes for CRISPR/Cas9 engineering of armoured CAR T cells with enhanced safety and efficacy
DOI: 10.1136/jitc-2025-sitc2025.0297
RECENT PROJECTS
2026
Research grants (ARC, NHMRC, MRFF)
Unraveling Metastasis-Specific Immune Niches to Transform Cancer Treatment
2024
Research grants (other domestic)
New Frontiers for CAR T Cell Therapy in Breast Cancer