Dr Michael Roche
Deputy Head, Lewin Lab
Department of Infectious Diseases
123 Scholarly works
15 Projects
HIGHLIGHTS
2026
Journal article
Targeting rapidly cycling receptors CD2 and CD7 increases nanoparticle delivery to primary CD4 T cells.
DOI: 10.1038/s41467-026-74981-22026
Journal article
HIV Promoters Isolated from Brain and Peripheral Tissue of Virally Suppressed PWH Are Phylogenetically and Functionally Similar
DOI: 10.3390/ijms270731852026
Journal article
Methaneseleninic acid, a circadian-modulating agent, reactivates latent HIV-1 infection without cellular activation or proliferation
DOI: 10.1128/jvi.01983-252026
Journal article
The effect of combining HIV latency reversal with inhibition of phosphoinositide-3 kinases or B-cell lymphoma-2 on the HIV reservoir
DOI: 10.1371/journal.ppat.10139232022
Research grants (international)
Targetted Delivery of LNP-encapsulated CRISPR/Cas9 for HIV Elimination
2021
Research grants (international)
Delaney AIDS Research Enterprise to Find a Cure (DARE 3.0) - (2021-2026) - SUBAWARD 7
2019
Research contracts (non-grants)
Victorian HIV Cure Consortium - Detecting Sites of Persistent HIV and Latency Reversal With Vorinostat and 64Cu Radiolabeled 3BNC117
RECENT SCHOLARLY WORKS
2025
Journal article
Limitations and use of the Morpheus-V5 dual reporter virus in assessing interventions that target HIV latency
DOI: 10.1016/j.jviromet.2025.1152362025
Journal article
The impact of acute stress on the HIV reservoir: a prospective interventional trial
DOI: 10.1016/j.jve.2025.1006132025
Journal article
Hepatitis B surface antigen is upregulated by HIV Tat in an HIV–hepatitis B virus co-infection model system
DOI: 10.1128/spectrum.00809-252025
Journal article
CRISPR/Cas9 for achieving postintervention HIV control
DOI: 10.1097/COH.00000000000009632025
Journal article
Host-directed approaches in the pursuit of a cure for HIV
DOI: 10.1016/j.antiviral.2025.1062162025
Journal article
Efficient mRNA delivery to resting T cells to reverse HIV latency
DOI: 10.1038/s41467-025-60001-2
RECENT PROJECTS
2025
Research grants (international)
Direct and Indirect Targeting of HIV Tat for Selective RNA Degradation and Protein Suppression
2026
Research grants (ARC, NHMRC, MRFF)
Leveraging mRNA and Lipid Nanoparticle Technology to Develop a Cure for HIV