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Email

michael.roche@unimelb.edu.au

Credentials


Position
Deputy Head, Lewin Lab
Department of Infectious Diseases
Education
PhD
Monash University
PhD
Monash University
Bachelors Degree
Deakin University
Bachelors Degree (Honours)
Monash University
ORCID

0000-0001-8819-0096

Dr Michael Roche

Deputy Head, Lewin Lab
Department of Infectious Diseases

122 Scholarly works
14 Projects

HIGHLIGHTS

  • 2026

    Journal article

    HIV Promoters Isolated from Brain and Peripheral Tissue of Virally Suppressed PWH Are Phylogenetically and Functionally Similar
    DOI: 10.3390/ijms27073185
  • 2026

    Journal article

    Methaneseleninic acid, a circadian-modulating agent, reactivates latent HIV-1 infection without cellular activation or proliferation
    DOI: 10.1128/jvi.01983-25
  • 2026

    Journal article

    The effect of combining HIV latency reversal with inhibition of phosphoinositide-3 kinases or B-cell lymphoma-2 on the HIV reservoir
    DOI: 10.1371/journal.ppat.1013923
  • 2025

    Journal article

    Limitations and use of the Morpheus-V5 dual reporter virus in assessing interventions that target HIV latency
    DOI: 10.1016/j.jviromet.2025.115236
  • 2022

    Research grants (international)

    Targetted Delivery of LNP-encapsulated CRISPR/Cas9 for HIV Elimination
  • 2021

    Research grants (international)

    Delaney AIDS Research Enterprise to Find a Cure (DARE 3.0) - (2021-2026) - SUBAWARD 7
  • 2017

    Research contracts (non-grants)

    Victorian HIV Cure Consortium
Michael Roche

RECENT SCHOLARLY WORKS

  • 2025

    Journal article

    The impact of acute stress on the HIV reservoir: a prospective interventional trial
    DOI: 10.1016/j.jve.2025.100613
  • 2025

    Journal article

    Hepatitis B surface antigen is upregulated by HIV Tat in an HIV–hepatitis B virus co-infection model system
    DOI: 10.1128/spectrum.00809-25
  • 2025

    Journal article

    CRISPR/Cas9 for achieving postintervention HIV control
    DOI: 10.1097/COH.0000000000000963
  • 2025

    Journal article

    Host-directed approaches in the pursuit of a cure for HIV
    DOI: 10.1016/j.antiviral.2025.106216
  • 2025

    Journal article

    Efficient mRNA delivery to resting T cells to reverse HIV latency
    DOI: 10.1038/s41467-025-60001-2
  • 2025

    Journal article

    Neuroinflammation associated with proviral DNA persists in the brain of virally suppressed people with HIV
    DOI: 10.3389/fimmu.2025.1570692

RECENT PROJECTS

  • 2025

    Research grants (international)

    Direct and Indirect Targeting of HIV Tat for Selective RNA Degradation and Protein Suppression
  • 2026

    Research grants (ARC, NHMRC, MRFF)

    Leveraging mRNA and Lipid Nanoparticle Technology to Develop a Cure for HIV

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