Prof Yugeesh Lankadeva
Honorary (Professorial Fellow)
Florey Department of Neuroscience and Mental Health
129 Scholarly works
13 Projects
HIGHLIGHTS
2026
Journal article
A preclinical randomised controlled dose optimization of megadose sodium ascorbate for reversal of gram-negative sepsis-induced cardiovascular, brain and kidney dysfunction
DOI: 10.1186/s13054-025-05799-52026
Journal article
Effects of glucagon-like peptide-1 on systemic hemodynamics, kidney function, and intrarenal oxygenation in sheep with sepsis-associated acute kidney injury
DOI: 10.1038/s41598-025-33109-02026
Journal article
A new murine gram-negative sepsis model with standard care satisfies Sepsis-3 and reproduces clinical pathology
DOI: 10.1186/s40635-026-00886-52026
Journal article
Sodium ascorbate versus ascorbic acid in sepsis: a narrative review of emerging cardiovascular and neurological benefits
DOI: 10.1186/s13054-025-05831-82025
Research grants (ARC, NHMRC, MRFF)
MEGA-dose Sodium Ascorbate to Reduce Brain and Kidney Injury Arising From HEART Surgery (MEGA-HEART)
2024
Research grants (ARC, NHMRC, MRFF)
Treating Tiny Tummies: Next Generation Cell Therapies for Paediatric Gut Disorders
2022
Research grants (ARC, NHMRC, MRFF)
Translating Novel Mechanism-Guided Therapeutics to Improve Functional Recovery of the Brain and Kidneys After Open-Heart Surgery
RECENT SCHOLARLY WORKS
2026
Journal article
An in-vitro study to characterise analytical interference caused by sodium ascorbate with point-of-care measurement of lactate and glucose
DOI: 10.1016/j.ccrj.2026.1001742026
Journal article
Reversal of cerebral ischaemia and hypoxia and of sickness behaviour by megadose sodium ascorbate in ovine Gram-negative sepsis. Response to Br J Anaesth 2026; 136: 781-2.
DOI: 10.1016/j.bja.2026.01.0132026
Journal article
Inflammation-Autonomic Crosstalk Contributes to Left Ventricular Diastolic Dysfunction in Type 2 Diabetes: A Rationale for Neuromodulation.
DOI: 10.1152/ajpheart.01006.20252026
Journal article
Effects of noradrenaline, vasopressin, phenylephrine or metaraminol on kidney and brain microcirculation in ovine cardiopulmonary bypass: a randomised trial
DOI: 10.1111/anae.700492026
Journal article
Cardiac surgery-associated acute kidney injury
DOI: 10.1016/j.bjae.2025.11.0012026
Journal article
3-dimensional morphological analysis of microglia in the sheep brain
DOI: 10.1016/j.jneumeth.2025.110624
RECENT PROJECTS
2024
Research grants (ARC, NHMRC, MRFF)
Targeted Therapies to Reduce Sepsis- And Heart Surgery-Associated Brain and Kidney Injury
2025
Research grants (other domestic)
Feasibility of Randomization to Different Flow Targets for Cardiopulmonary Bypass