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Email

nichollas.scott@unimelb.edu.au

Credentials


Position
Principal Research Fellow
Department of Microbiology and Immunology
Education
PhD
University of Sydney
Bachelors Degree (Honours)
University of Sydney
ORCID

0000-0003-2556-8316

A/Prof Nichollas Scott

Principal Research Fellow
Department of Microbiology and Immunology

155 Scholarly works
25 Projects

HIGHLIGHTS

  • 2026

    Journal article

    Dual membrane-spanning anti-sigma 2 controls OMV biogenesis and colonization fitness in Bacteroides thetaiotaomicron.
    DOI: 10.1128/jb.00442-25
  • 2026

    Journal article

    Trigger Factor in Burkholderia pseudomallei is essential for key virulence determinants, including host cell internalization, cytotoxicity, motility, and stress resistance.
    DOI: 10.1128/jb.00124-26
  • 2026

    Journal article

    Uncovering bacterial pseudaminylation with pan-specific antibody tools
    DOI: 10.1038/s41589-025-02114-9
  • 2026

    Journal article

    Advances in degradomics technologies to assess proteolytic cleavage events
    DOI: 10.1016/j.chembiol.2026.01.001
  • 2025

    Research grants (other domestic)

    Near Single Molecule Sensitivity Mass Spectrometry for Multi-Omic Research
  • 2021

    Research grants (ARC, NHMRC, MRFF)

    Characterising O-Linked Glycosylation Across Burkholderia
  • 2021

    Research grants (ARC, NHMRC, MRFF)

    How Does Glycosylation Shape Protein Function Within Burkholderia?
Nichollas Scott

Latest Honours,
Awards and Fellowships


2021
Australian Society for Microbiology Frank Fenner Award
2021
ARC Future Fellow
2019
Young Glycoscientist Award. Awarded by International Glycoconjugate Organization.
2018
CASS Foundation Travel Award. Awarded by Cass Foundation

RECENT SCHOLARLY WORKS

  • 2026

    Journal article

    Intralysosomal pathogens differentially influence the proteolytic potential of their niche
    DOI: 10.1128/iai.00270-25
  • 2026

    Journal article

    Enhancing O-linking oligosaccharyltransferase functionality through directed evolution
    DOI: 10.1016/j.jbc.2025.110885
  • 2025

    Journal article

    Bridging a Gap in Marine Sulfur Cycling: Discovery of a d-Cysteinolic Acid Degradation Pathway
    DOI: 10.1021/jacs.5c11066
  • 2025

    Journal article

    Intracellular Acinetobacter baumannii acts as a transient reservoir in lung infection via a “persist and resist” strategy
    DOI: 10.1073/pnas.2511369122
  • 2025

    Journal article

    A multivalent capsule vaccine protects against Klebsiella pneumoniae bloodstream infections in healthy and immunocompromised mice
    DOI: 10.1038/s41541-025-01314-7
  • 2025

    Journal article

    Glycoproteomics and Its Role in Understanding Bacterial O-Linked Glycosylation
    DOI: 10.1002/pmic.202400256

RECENT PROJECTS

  • 2026

    Research contracts (non-grants)

    Glycosylation Analysis of Recombinant Proteins for Omniose
  • 2024

    Research grants (other domestic)

    Harnessing Burkholderia O-Linked Glycosylation to Generate Passive Immunotherapies for Burkholderia Infections.

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