Dr. Stanley Xie
Research Assistant
Biochemistry and Pharmacology
13 Scholarly works
1 Projects
HIGHLIGHTS
2020
Journal article
K13, the Cytostome, and Artemisinin Resistance
DOI: 10.1016/j.pt.2020.03.0062019
Journal article
Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance
DOI: 10.1016/j.celrep.2019.10.0952019
Journal article
The proteasome as a target for protozoan parasites
DOI: 10.1080/14728222.2019.16859812019
Journal article
The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis
DOI: 10.1038/s41564-019-0524-42018
Journal article
Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome
DOI: 10.1021/acs.jmedchem.8b011612018
Journal article
Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome
DOI: 10.1038/s41467-018-06221-12016
Research Contracts
Participation as a Visiting Scientist -opportunity to participate as a visiting scientist in certain scientific activities of Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited,
RECENT SCHOLARLY WORKS
2017
Journal article
A Dynamic Stress Model Explains the Delayed Drug Effect in Artemisinin Treatment of Plasmodium falciparum
DOI: 10.1128/AAC.00618-172016
Journal article
Comparison of the Exposure Time Dependence of the Activities of Synthetic Ozonide Antimalarials and Dihydroartemisinin against K13 Wild-Type and Mutant Plasmodium falciparum Strains
DOI: 10.1128/AAC.00574-162016
Journal article
Structure- and function-based design of Plasmodium-selective proteasome inhibitors
DOI: 10.1038/nature169362016
Journal article
Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins
DOI: 10.1242/jcs.1788302015
Journal article
Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance
DOI: 10.1371/journal.pbio.10021322014
Journal article
Optimal assay design for determining the in vitro sensitivity of ring stage Plasmodium falciparum to artemisinins
DOI: 10.1016/j.ijpara.2014.07.0082013
Journal article
Altered temporal response of malaria parasites determines differential sensitivity to artemisinin
DOI: 10.1073/pnas.1217452110