Dr Najoua Lalaoui
Honorary Conjoint Senior Fellow
The Sir Peter MacCallum Department of Oncology
22 Scholarly works
2 Projects
HIGHLIGHTS
2026
Journal article
Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia
DOI: 10.1016/j.cell.2025.10.0282025
Journal article
Divergent roles of RIPK3 and MLKL in high-fat diet–induced obesity and MAFLD in mice
DOI: 10.26508/lsa.2023024462024
Journal article
Dominant negative OTULIN-related autoinflammatory syndrome
DOI: 10.1084/jem.202221712024
Journal article
RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation
DOI: 10.1038/s41418-024-01281-x2023
Research grants (ARC, NHMRC, MRFF)
Investigating the Interplay Between Cell Death and Inflammation in Human Diseases
2018
Research Grant
Novel Therapies to Enhance Anti-Tumour Immunity
2014
Journal article
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
DOI: 10.1016/j.cell.2014.04.019
RECENT SCHOLARLY WORKS
2024
Journal article
Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency
DOI: 10.1038/s41590-024-01817-w2023
Journal article
A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation
DOI: 10.15252/embr.2023568652023
Journal article
RIPK3 controls MAIT cell accumulation during development but not during infection
DOI: 10.1038/s41419-023-05619-02022
Journal article
Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
DOI: 10.1016/j.isci.2022.1046322022
Journal article
Langerhans cells are an essential cellular intermediary in chronic dermatitis
DOI: 10.1016/j.celrep.2022.1109222021
Journal article
The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis
DOI: 10.1038/s41419-021-03418-z