Prof Sean Grimmond
Director, Collaborative Centre for Cancer Genomics
Centre for Cancer Research
413 Scholarly works
35 Projects
HIGHLIGHTS
2025
Journal article
Perioperative IDH inhibition in treatment-naive IDH-mutant glioma: a pilot trial
DOI: 10.1038/s41591-025-03884-42020
Research grants (ARC, NHMRC, MRFF)
Super-Next: Complete Genome Profiling for Cancer of Unknown Primary
2020
Research grants (ARC, NHMRC, MRFF)
Evaluation of Fibroblastic Activation Protein Inhibitors (FAPI) as a Novel Radiopharmaceutical Targeting Cancer-Associated Fibroblasts for the Diagnosis and Treatment of Patients With Cancer of Unknown Primary: The FAPI-CUP Trial
2020
Research grants (ARC, NHMRC, MRFF)
Dissecting the Mutational Landscapes, Cellular Ecosystems and Therapeutic Vulnerabilities of Pancreatic Cancer
2015
Journal article
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
DOI: 10.1038/ncomms100012015
Journal article
Whole-genome characterization of chemoresistant ovarian cancer
DOI: 10.1038/nature144102015
Journal article
Whole genomes redefine the mutational landscape of pancreatic cancer
DOI: 10.1038/nature14169
RECENT SCHOLARLY WORKS
2026
Journal article
Abstract 7282: A comprehensive multiomics atlas of treatment-naïve breast cancer uncovers co-occurring tumor-immune ecosystems driving immune hot and cold phenotypes
DOI: 10.1158/1538-7445.am2026-72822026
Journal article
Abstract 44: scSubtype2.0: Predictor of breast cancer molecular subtypes at single cell resolution.
DOI: 10.1158/1538-7445.am2026-442026
Journal article
Endoscopic ultrasound molecular evaluation of pancreatic cancer trial to profile molecular landscape of inoperable pancreatic ductal adenocarcinoma.
DOI: 10.1055/a-2733-10682026
Journal article
KRAS internal tandem duplications and alternative driver variants in BRAF Val600Glu negative hairy cell leukemia
DOI: 10.1080/10428194.2026.26150552025
Journal article
Abstract B023: Temporally resolved proteomics identifies nidogen-2 as a co-target in pancreatic cancer that modulates fibrosis and therapy response
DOI: 10.1158/1538-7445.canevol25-b0232025
Journal article
762MO Clinical whole genome and transcriptome sequencing for cancer of unknown primary: An Australian prospective observational study
DOI: 10.1016/j.annonc.2025.10.11772025
Journal article
Pathologist-initiated whole genome and transcriptome sequencing demonstrates diagnostic utility in resolving difficult-to-diagnose tumors
DOI: 10.1186/s13073-025-01534-52025
Journal article
Automated integration of multi-slice spatial transcriptomics data in 2D and 3D using VR-Omics
DOI: 10.1186/s13059-025-03630-6