Mrs Behnaz Heydarchi
Honorary (Fellow)
Department of Medical Biology (WEHI)
21 Scholarly works
4 Projects
HIGHLIGHTS
2025
Journal article
Fc mutagenesis enhances the functionality of anti-RhD monoclonal antibodies
DOI: 10.1182/bloodadvances.20240150822022
Journal article
Protocol for production and expression of chimeric bovine-human monoclonal antibodies
DOI: 10.1016/j.xpro.2022.1019112022
Journal article
Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody
DOI: 10.1016/j.xcrm.2022.1006352021
Journal article
Enhancement of antibody-dependent cellular cytotoxicity and phagocytosis in anti-HIV-1 human-bovine chimeric broadly neutralizing antibodies
DOI: 10.1128/JVI.00219-212021
Conference Proceedings
Monoclonal antibodies with ultra-long CDRH3 derived from vaccinated cows show exceptional neutralisation potency and breadth that is retained after Fc engineering
2021
Conference Proceedings
A lineage of exceptionally potent and broad BnAbs with ultralong CDRH3 from vaccinated cows focus low-mutation rate from germline into a globular knob contacting the CD4bs
2018
Research Contracts
Antibody-Based HIV Prevention
RECENT SCHOLARLY WORKS
2018
Conference Proceedings
HIV-1 Env Trimers Eliciting Antibody With Neutralising and Cellular-dependent Functions in Vaccinated Cows
2018
Conference Proceedings
HIV Neutralising Monoclonal Antibodies With Optimised Antibody Effector Functions
2017
Journal article
Trimeric gp120-specific bovine monoclonal antibodies require cysteine and aromatic residues in CDRH3 for high affinity binding to HIV Env
DOI: 10.1080/19420862.2016.12704912016
Journal article
Repeated vaccination of cows with HIV env gp140 during subsequent pregnancies elicits and sustains an enduring strong env-binding and neutralising antibody response
DOI: 10.1371/journal.pone.0157353
RECENT PROJECTS
2023
Research Grant
Unmasking HIV-1 Neutralisation Mechanism of an Ultra-Potent HIV Neutralising Monoclonal Antibody
2017
Research Contracts
Victorian Hiv Cure
2019
Research Grant
Humanisation of Broadly Neutralising Bovine Monoclonal Antibodies for Hiv Cure And Prevention