A/Prof Vihandha Wickramasinghe
Principal Research Fellow
Department of Biochemistry and Pharmacology
22 Scholarly works
8 Projects
HIGHLIGHTS
2025
Journal article
mRNA export factors store nascent transcripts within nuclear speckles as an adaptive response to transient global inhibition of transcription
DOI: 10.1016/j.molcel.2024.12.0082025
Research grants (ARC, NHMRC, MRFF)
Circular RNA Transport and Function
2024
Journal article
Prediction of m6A and m5C at single-molecule resolution reveals a transcriptome-wide co-occurrence of RNA modifications
DOI: 10.1038/s41467-024-47953-72024
Journal article
Nuclear export of circular RNA
DOI: 10.1038/s41586-024-07060-52022
Journal article
Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAFV600 melanoma
DOI: 10.1038/s41467-022-28705-x2021
Research grants (ARC, NHMRC, MRFF)
Exploiting Messenger RNA Export as a Novel Therapeutic Strategy to Treat Cancer
2021
Research grants (ARC, NHMRC, MRFF)
Pathways That Regulate Nuclear Export of Circular RNA
RECENT SCHOLARLY WORKS
2022
Journal article
Pathogenic variants in nucleoporin TPR (translocated promoter region, nuclear basket protein) cause severe intellectual disability in humans
DOI: 10.1093/hmg/ddab2482021
Journal article
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
DOI: 10.1016/j.molcel.2021.04.0152021
Journal article
RNA in cancer
DOI: 10.1038/s41568-020-00306-02020
Journal article
Germline heterozygous mutations in Nxf1 perturb RNA metabolism and trigger thrombocytopenia and lymphopenia in mice
DOI: 10.1182/bloodadvances.20190013232019
Journal article
A systems view of spliceosomal assembly and branchpoints with iCLIP
DOI: 10.1038/s41594-019-0300-42019
Conference Proceedings
Complex-centric proteome profiling by SEC-SWATH-MS
RECENT PROJECTS
2025
Research grants (ARC, NHMRC, MRFF)
Circular RNA Transport and Function
2019
Research Contracts
Salary Contribution - Ci DR Vihandha Wickramsinghe - Teaching Bcmb30002 Functional Genomics and Bioinformatics