A/Prof Kristin Brown
Principal Research Fellow
Department of Biochemistry and Pharmacology
53 Scholarly works
5 Projects
HIGHLIGHTS
2026
Journal article
A multi-omic approach reveals iron availability influences cell fate fidelity
DOI: 10.1038/s44324-026-00102-82026
Journal article
Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia
DOI: 10.1016/j.cell.2025.10.0282025
Journal article
Relative importance of the anti-apoptotic versus apoptosis-unrelated functions of MCL-1 invivo
DOI: 10.1126/science.adw18362025
Journal article
Genome-wide in vivo CRISPR screens identify GATOR1 complex as a tumor suppressor in Myc-driven lymphoma
DOI: 10.1038/s41467-025-62615-y2022
Research grants (ARC, NHMRC, MRFF)
Investigating the Role of Cellular Metabolism in Regulating Antigen Presentation and Tumour Immune Escape
2021
Research Grant
Investigating the Consequences of Dysregulated Lipogenesis in Cancer
2018
Research Grant
Interplay Between Metabolic Reprogramming and Oncogenic Signalling in the Cellular Response to Chemotherapy
RECENT SCHOLARLY WORKS
2024
Journal article
3099 – HEME BIOSYNTHESIS IS A THERAPEUTIC VULNERABILITY IN ACUTE MYELOID LEUKAEMIA
DOI: 10.1016/j.exphem.2024.1044212024
Conference Proceedings
HEME BIOSYNTHESIS IS A THERAPEUTIC VULNERABILITY IN ACUTE MYELOID LEUKAEMIA
2024
Conference Proceedings
HEME BIOSYNTHESIS IS A THERAPEUTIC VULNERABILITY IN ACUTE MYELOID LEUKAEMIA
2024
Journal article
SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway
DOI: 10.1016/j.devcel.2024.01.0242023
Journal article
The KEAP1–NRF2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis
DOI: 10.1073/pnas.22174251202023
Other
Supplementary Figure from Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death
DOI: 10.1158/2159-8290.22540945.v1
RECENT PROJECTS
2018
Research grants (other domestic)
Targeting Cell Metabolism to Improve the Treatment of Triple-Negative Breast Cancer
2018
Research grants (international)
Targeting Cell Metabolism to Circumvent Chemotherapy Resistance in TNBC