Contact

Address

03, 364, David Penington Building, Parkville

Phone

+61390354902

Email

isabelle.rouiller@unimelb.edu.au

Credentials

Position
Assoc Professor (Structural Biologist)
Biochemistry and Molecular Biology
Education
Doctor of Philosphy
University of Hertfordshire
Engineer Biochemistry
Institut National des Sciences Appliquees
DEA Biochemistry
Universite Claude Bernard Lydon 1
ORCID

0000-0002-1288-8575

A/Prof. Isabelle Rouiller

Assoc Professor (Structural Biologist)
Biochemistry and Molecular Biology
55 Scholarly works
6 Projects

HIGHLIGHTS

  • 2021

    Research Grant

    Structure and mechanism of activation of the mechanosensitive ion channel TACAN
  • 2020

    Journal article

    A "Drug Sweeping" State of the TriABC Triclosan Efflux Pump from Pseudomonas aeruginosa.
    DOI: 10.1016/j.str.2020.09.001
  • 2020

    Research Grant

    Lysine acetylation as switch for Optic Atrophy 1 inactivation
  • 2020

    Research Grant

    MOLECULAR BASIS OF ZINC ACQUISITION BY STREPTOCOCCUS PNEUMONIAE
  • 2019

    Journal article

    Plant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages
    DOI: 10.1038/s41541-019-0111-y
  • 2019

    Journal article

    An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity
    DOI: 10.1016/j.chom.2019.03.002
  • 2018

    Journal article

    The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution
    DOI: 10.7554/eLife.34085
Isabelle Rouiller

Latest Honours,
Awards and Fellowships

2008
Salary award (2007-2012) Canadian Institutes of Health Research (CIHR)
2007
National award for lab set-up, New Opportunities Fund Award Canada Foundation for Innovation
2008
Canadian Institutes of Health Research (CIHR) New Investigator Salary Award (2008-2013)
2007
Canada Foundation for Innovation, New Opportunities Fund Award (2007)

RECENT SCHOLARLY WORKS

  • 2018

    Journal article

    Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy
    DOI: 10.7554/eLife.32866
  • 2018

    Journal article

    Morphological characterization of a plant-made virus-like particle vaccine bearing influenza virus hemagglutinins by electron microscopy
    DOI: 10.1016/j.vaccine.2018.02.106
  • 2017

    Journal article

    Molecular mechanism of DRP1 assembly studied in vitro by cryo-electron microscopy
    DOI: 10.1371/journal.pone.0179397
  • 2017

    Journal article

    Negative Stain Single-particle EM of the Maltose Transporter in Nanodiscs Reveals Asymmetric Closure of MalK(2) and Catalytic Roles of ATP, MalE, and Maltose
    DOI: 10.1074/jbc.M116.757898
  • 2016

    Journal article

    Structure-Function Profile of MmpL3, the Essential Mycolic Acid Transporter from Mycobacterium tuberculosis
    DOI: 10.1021/acsinfecdis.6b00095
  • 2016

    Journal article

    Structure of anthrax lethal toxin prepore complex suggests a pathway for efficient cell entry
    DOI: 10.1085/jgp.201611617
  • 2016

    Journal article

    Molecular assembly of lethal factor enzyme and pre-pore heptameric protective antigen in early stage of translocation
    DOI: 10.1007/s00894-015-2878-8
  • 2015

    Journal article

    Cryo-EM of the pathogenic VCP variant R155P reveals long-range conformational changes in the D2 ATPase ring
    DOI: 10.1016/j.bbrc.2015.11.003