Dr Michelle Christie
Research Fellow
Department of Biochemistry and Pharmacology
26 Scholarly works
1 Projects
HIGHLIGHTS
2025
Journal article
Structural basis for the pore-forming activity of a complement-like toxin
DOI: 10.1126/sciadv.adt21272024
Journal article
Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria
DOI: 10.1038/s41467-024-49103-52024
Journal article
Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure
DOI: 10.7554/eLife.836052023
Journal article
Deciphering the early stages of pore formation in the cholesterol-dependent cytolysins
DOI: 10.1107/s205327332308943x2022
Journal article
Cholesterol-dependent cytolysins: The outstanding questions
DOI: 10.1002/iub.26612022
Thesis / Dissertation
Using structural biology to understand how bacterial toxins exert their activity
2020
Research Contracts
Id9654 - Ricin Medical Countermeasure Structural Analysis
RECENT SCHOLARLY WORKS
2022
Journal article
Single-molecule analysis of the entire perfringolysin O pore formation pathway
DOI: 10.7554/eLife.749012021
Journal article
Two-component pore formation by the novel CDCL proteins ALY short and ALY long from Elizabethkingia anophelis
DOI: 10.1107/s01087673210920472021
Book Chapter
X-ray crystallography shines a light on pore-forming toxins
DOI: 10.1016/bs.mie.2021.01.0012020
Journal article
A key motif in the cholesterol-dependent cytolysins reveals a large family of related proteins
DOI: 10.1128/mBio.02351-202019
Journal article
The structural basis for a transition state that regulates pore formation in a bacterial toxin
DOI: 10.1128/mBio.00538-19