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Email

michelle.christie@unimelb.edu.au

Credentials


Position
Research Fellow
Department of Biochemistry and Pharmacology
Education
Doctoral Degree (Research) / PhD
The University of Queensland
Masters Degree (Research)
The University of Queensland
Masters Degree (Coursework)
University of Peradeniya
Bachelors Degree
Bangalore University
ORCID

0000-0002-7001-3400

Dr Michelle Christie

Research Fellow
Department of Biochemistry and Pharmacology

26 Scholarly works
1 Projects

HIGHLIGHTS

  • 2025

    Journal article

    Structural basis for the pore-forming activity of a complement-like toxin
    DOI: 10.1126/sciadv.adt2127
  • 2024

    Journal article

    Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria
    DOI: 10.1038/s41467-024-49103-5
  • 2024

    Journal article

    Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure
    DOI: 10.7554/eLife.83605
  • 2023

    Journal article

    Deciphering the early stages of pore formation in the cholesterol-dependent cytolysins
    DOI: 10.1107/s205327332308943x
  • 2022

    Journal article

    Cholesterol-dependent cytolysins: The outstanding questions
    DOI: 10.1002/iub.2661
  • 2022

    Thesis / Dissertation

    Using structural biology to understand how bacterial toxins exert their activity
  • 2020

    Research Contracts

    Id9654 - Ricin Medical Countermeasure Structural Analysis
Michelle Christie

RECENT SCHOLARLY WORKS

  • 2022

    Journal article

    Single-molecule analysis of the entire perfringolysin O pore formation pathway
    DOI: 10.7554/eLife.74901
  • 2021

    Journal article

    Two-component pore formation by the novel CDCL proteins ALY short and ALY long from Elizabethkingia anophelis
    DOI: 10.1107/s0108767321092047
  • 2021

    Book Chapter

    X-ray crystallography shines a light on pore-forming toxins
    DOI: 10.1016/bs.mie.2021.01.001
  • 2020

    Journal article

    A key motif in the cholesterol-dependent cytolysins reveals a large family of related proteins
    DOI: 10.1128/mBio.02351-20
  • 2019

    Journal article

    The structural basis for a transition state that regulates pore formation in a bacterial toxin
    DOI: 10.1128/mBio.00538-19

Acknowledgement of Country

We acknowledge Aboriginal and Torres Strait Islander people as the Traditional Owners of the unceded lands on which we work, learn and live. We pay respect to Elders past, present and future, and acknowledge the importance of Indigenous knowledge in the Academy.

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