A/Prof Ian Parish
Honorary Conjoint Principal Fellow
The Sir Peter MacCallum Department of Oncology
68 Scholarly works
11 Projects
HIGHLIGHTS
2026
Journal article
High efficiency CRISPR knock-in demonstrates that TCF1 is insufficient to reverse T cell exhaustion
DOI: 10.1038/s41467-026-69671-y2026
Journal article
Fine-tuning BACH2 dosage balances stemness and effector function to enhance antitumor T cell therapy
DOI: 10.1038/s41590-025-02389-z2026
Journal article
Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8 T cells in lymph nodes
DOI: 10.1038/s41590-026-02419-42026
Research grants (ARC, NHMRC, MRFF)
Breaking the Rules of T Cell Biology to Improve Cancer Treatment
2025
Journal article
Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
DOI: 10.1038/s41467-025-59021-92022
Research grants (other domestic)
Leveraging mRNA Technology to Improve Adoptive Cell Therapy for Cancer
2021
Research grants (ARC, NHMRC, MRFF)
Repurposing Thalidomide Derivatives to Augment Cancer Immunotherapy
RECENT SCHOLARLY WORKS
2025
Journal article
Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution
DOI: 10.1038/s41467-025-59500-z2025
Journal article
Retraction Notice to “Aberrant CD8 T-Cell Responses and Memory Differentiation upon Viral Infection of an Ataxia-Telangiectasia Mouse Model Driven by Hyper-Activated Akt and mTORC1 Signaling” [Am J Pathol 178 (2011) 2740–2751, (S000294401100229X), (10.1016/j.ajpath.2011.02.022)]
DOI: 10.1016/j.ajpath.2025.08.0022025
Journal article
The high (I)COSt of costimulation for exhausted T cells
DOI: 10.1016/j.immuni.2025.07.0102025
Journal article
Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery
DOI: 10.1038/s41586-025-09212-72025
Journal article
Multivalent Presentation of TCRs on DNA Nanostructures as a Sensitive Probe for pMHC Detection
DOI: 10.1021/acsanm.5c012962024
Journal article
The CD8 T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
DOI: 10.1016/j.immuni.2024.04.026
RECENT PROJECTS
2026
Research grants (ARC, NHMRC, MRFF)
Unraveling Metastasis-Specific Immune Niches to Transform Cancer Treatment
2025
Research grants (international)
Decoding the Epigenetic Switches Controlling Early Fate Decisions in CD8+ T Cells