A/Prof Laura Edgington-Mitchell
Associate Professor in Biochemistry & Pharmacology
Department of Biochemistry and Pharmacology
92 Scholarly works
8 Projects
HIGHLIGHTS
2026
Journal article
Probing the activity of cysteine cathepsins in inflammatory bowel diseases
DOI: 10.1038/s41598-025-32489-72026
Journal article
Integration of Chemical Probes and Degradomics Reveals That Cathepsin B Functions Primarily as a Dipeptidyl Carboxypeptidase in Macrophages.
DOI: 10.1002/cmdc.705302026
Journal article
Defining the Role of Dipeptidyl Peptidase-1 in Murine Lung Immune Regulation
DOI: 10.1055/s-0046-18260532026
Journal article
Endothelial C/EBPβ/AEP pathway drives vascular deterioration and systemic aging.
DOI: 10.1126/sciadv.aed19612026
Research grants (other domestic)
ThermoFisher Orbitrap ASTRAL Zoom
2025
Research grants (ARC, NHMRC, MRFF)
Legumain at the Cutting Edge of Oral Cancer
2018
Research Grant
Novel Chemical Tools to Study Cathepsin X Activation
RECENT SCHOLARLY WORKS
2026
Journal article
PAC/SP3 On-Bead Carboxyl Derivatization Allows Combined C- and N-Terminomics
DOI: 10.1021/acs.analchem.6c019382026
Journal article
Mast cell proteases and their significance in physiology, pathology, and therapeutic approaches
DOI: 10.1016/j.pharmr.2026.1001442026
Journal article
Advances in degradomics technologies to assess proteolytic cleavage events
DOI: 10.1016/j.chembiol.2026.01.0012026
Journal article
When Neutrophils Go Rogue: Dysregulated Inflammation in Airway Diseases and Implications for Therapy
DOI: 10.1021/acsptsci.5c006402026
Journal article
Intralysosomal pathogens differentially influence the proteolytic potential of their niche
DOI: 10.1128/iai.00270-252026
Journal article
Electrophysiological and Proteomic Evidence of Protease-Mediated Pro-nociceptive Signaling in Inflammatory Bowel Disease Patients
DOI: 10.1523/JNEUROSCI.0220-25.2025
RECENT PROJECTS
2026
Research grants (ARC, NHMRC, MRFF)
Pathogen-Mediated Manipulation of the Human Lysosome: A Target for Infection Control
2026
Research grants (other domestic)
2026 Research Impetus Grants