Dr Lorey K Smith
Honorary Conjoint Fellow
The Sir Peter MacCallum Department of Oncology
28 Scholarly works
4 Projects
HIGHLIGHTS
2025
Journal article
Sensitivity to immune checkpoint inhibitors in BRAF/MEK inhibitor refractory melanoma
DOI: 10.1136/jitc-2025-0115512025
Journal article
Ubiquitous expression of an activating mutation in the Pik3ca gene reprograms glucose and lipid metabolism in mice
DOI: 10.1371/journal.pone.03225442025
Journal article
BRAF/MEK inhibition following immune checkpoint inhibitors promotes antitumor immunity associated with expansion of progenitor-exhausted CD8⁺ T cells
DOI: 10.1016/j.ejcskn.2025.1007372023
Research grants (international)
Investigating Transcript Diversity as a Driver of Melanoma Progression and Recurrence
2023
Journal article
The therapeutic potential of targeting minimal residual disease in melanoma
DOI: 10.1002/ctm2.11972023
Research grants (other domestic)
Preventing Emergence of Therapy Resistance in Melanoma
2020
Research Grant
Overcoming Therapy Induced Reprogramming of Metabolism in Cancer
RECENT SCHOLARLY WORKS
2022
Journal article
Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAFV600 melanoma
DOI: 10.1038/s41467-022-28705-x2022
Journal article
Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway
DOI: 10.1016/j.celrep.2022.1115712022
Journal article
Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia
DOI: 10.15252/emmm.2021152032022
Journal article
Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death
DOI: 10.1158/2159-8290.CD-21-05222021
Journal article
Enhancing adoptive cell transfer with combination braf-mek and cdk4/6 inhibitors in melanoma
DOI: 10.3390/cancers132463422021
Journal article
Metabolic plasticity in melanoma progression and response to oncogene targeted therapies
DOI: 10.3390/cancers13225810
RECENT PROJECTS
2023
Research grants (other domestic)
Preventing Emergence of Therapy Resistance in Melanoma