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Email

bezaworkgeleta.a@unimelb.edu.au

Credentials


Position
IT Access
Department of Anatomy and Physiology
Education
Doctorate (Research)
La Trobe University
ORCID

0000-0003-2739-8023

Dr Ayenachew Bezawork-Geleta

Honorary Fellow
Faculty of Medicine, Dentistry and Health Sciences

28 Scholarly works
3 Projects

HIGHLIGHTS

  • 2020

    Research Grant

    New Therapies for High-Risk Primary Brain Cancer Glioblastoma
  • 2019

    Journal article

    Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells
    DOI: 10.1016/j.cmet.2018.10.014
  • 2018

    Journal article

    Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints
    DOI: 10.1038/s41467-018-04603-z
  • 2017

    Journal article

    Mitochondrial Complex II: At the Crossroads
    DOI: 10.1016/j.tibs.2017.01.003
  • 2017

    Journal article

    Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells
    DOI: 10.7554/eLife.22187
  • 2017

    Journal article

    Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer
    DOI: 10.1089/ars.2016.6677
  • 2016

    Journal article

    The assembly factor SDHAF2 is dispensable for flavination of the catalytic subunit of mitochondrial complex II in breast cancer cells
    DOI: 10.1074/jbc.C116.755017
Ayenachew Bezawork-Geleta

Latest Honours,
Awards and Fellowships


2021
2021 DAP ECR seeding grant Department of Anatomy and Physiology
2021
2021 MDHS Seeding Ideas Grants MDHS
2016
The Societies for Free Radical Research Australasia and Japan
2016
The International Union of Biochemistry and Molecular Biology (IUBMB, Vancouver, Canada)

RECENT SCHOLARLY WORKS

  • 2025

    Journal article

    Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites
    DOI: 10.1038/s41467-025-57405-5
  • 2024

    Journal article

    Metabolic Plasticity of Glioblastoma Cells in Response to DHODH Inhibitor BAY2402234 Treatment
    DOI: 10.3390/metabo14080413
  • 2023

    Journal article

    The Interleukin-11/IL-11 Receptor Promotes Glioblastoma Survival and Invasion under Glucose-Starved Conditions through Enhanced Glutaminolysis
    DOI: 10.3390/ijms24043356
  • 2022

    Journal article

    Lipid droplets and ferroptosis as new players in brain cancer glioblastoma progression and therapeutic resistance
    DOI: 10.3389/fonc.2022.1085034
  • 2020

    Journal article

    SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control
    DOI: 10.1126/SCITRANSLMED.AAZ8048
  • 2019

    Conference Proceedings

    Human pheochromocytoma cancer cells as a plausible model of mitochondrial complex II-linked tumorigenesis
  • 2018

    Conference Proceedings

    Alternate assembly of SDHA regulates energy balance under bioenergetic stress
  • 2018

    Journal article

    Affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism
    DOI: 10.1038/s41556-017-0023-x

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