Dr Samantha Barton
Honorary Senior Fellow
Florey Department of Neuroscience and Mental Health
9 Scholarly works
6 Projects
HIGHLIGHTS
2025
Journal article
Schwann cells as a therapeutic target for amyotrophic lateral sclerosis: A TDP-43 focussed review
DOI: 10.1016/j.neuint.2025.1060552025
Journal article
Cortical hyperexcitability drives dying forward amyotrophic lateral sclerosis symptoms and pathology in mice
DOI: 10.1016/j.pneurobio.2025.1028092024
Journal article
Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration
DOI: 10.1016/j.cell.2024.04.0052023
Research grants (ARC, NHMRC, MRFF)
WNT Signalling in Oligodendroglia: A Missing Link in MS Neuroinflammation
2022
Journal article
Lipid Metabolism Is Dysregulated in the Motor Cortex White Matter in Amyotrophic Lateral Sclerosis
DOI: 10.3390/metabo120605542022
Research grants (ARC, NHMRC, MRFF)
Are Oligodendrocytes the Missing Link in Amyotrophic Lateral Sclerosis Pathogenesis?
2021
Research Grant
Development of Blood-Brain Barrier Penetrating Peptides as a CNS Drug Delivery Platform
RECENT SCHOLARLY WORKS
2022
Journal article
Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis
DOI: 10.1038/s41418-021-00910-z2022
Journal article
α-Amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor and RNA processing gene dysregulation are early determinants of selective motor neuron vulnerability in a mouse model of amyotrophic lateral sclerosis
DOI: 10.1093/braincomms/fcac0812020
Journal article
Mutant TDP-43 Expression Triggers TDP-43 Pathology and Cell Autonomous Effects on Primary Astrocytes: Implications for Non-cell Autonomous Pathology in ALS
DOI: 10.1007/s11064-020-03048-52019
Journal article
Could an impairment in local translation of mRNAs in glia be contributing to pathogenesis in ALS?
DOI: 10.3389/fnmol.2019.001242019
Journal article
Dose-dependent exacerbation of ventilation-induced lung injury by erythropoietin in preterm newborn lambs
DOI: 10.1152/japplphysiol.00800.2018
RECENT PROJECTS
2027
Research grants (ARC, NHMRC, MRFF)
Using iPSC-derived Organoids to Understand Remyelination in Multiple Sclerosis
2025
Research grants (other domestic)
Identifying Drivers of Neuronal Dysfunction by Studying Myelinated Axons in iPSC-derived Organoids
2021
Research Grant
Lipidomic Signatures in Blood as a Novel Biomarker for MND