Prof Brian Dean
Honorary (Professorial Fellow)
Department of Psychiatry
555 Scholarly works
16 Projects
HIGHLIGHTS
2025
Journal article
Exon-variant interplay and multi-modal evidence identify endocrine dysregulation in severe psychiatric disorders impacting excitatory neurons
DOI: 10.1038/s41398-025-03366-82025
Journal article
Changes in the Blood Transcriptome Highlights Disturbed Peripheral Biochemical Homeostasis in Bipolar Disorder
DOI: 10.1111/bdi.700582025
Conference Proceedings
591. Muscarinic receptors and the molecular pathology of schizophrenia
DOI: 10.1093/ijnp/pyaf052.3792025
Journal article
Elucidating Molecular Mechanisms of Drug-Induced Hepatotoxicity of Lapatinib.
DOI: 10.1021/acs.jmedchem.5c013052025
Conference Proceedings
249. Elevated levels of akt-interacting protein in the frontal pole reveals molecular pathology specific to a subtype of people with schizophrenia
DOI: 10.1093/ijnp/pyaf052.0332025
Journal article
Optimizing the discovery bioanalysis strategy for macrocyclic peptides.
DOI: 10.1007/s00216-025-05781-82018
Internal Research Grant
Characterising the Muscarinic Receptor Deficit in Schizophrenia
RECENT SCHOLARLY WORKS
2025
Journal article
Glutamate concentrations and cognitive deficits in ultra-treatment-resistant schizophrenia: An exploratory and comparative 1H-MRS study
DOI: 10.1016/j.pscychresns.2024.1119262025
Journal article
Identification of isomeric glucuronides by electronic excitation dissociation tandem mass spectrometry
DOI: 10.1016/j.ijms.2024.1173722024
Journal article
Lower levels of kainate receptors, but not AMPA or NMDA receptors, in Brodmann's area (BA) 9, but not BA 10, from a subgroup of people with schizophrenia who have a marked deficit in cortical muscarinic M1 receptors
DOI: 10.1016/j.schres.2024.09.0142024
Journal article
IUPHAR Review on muscarinic M1 and M4 receptors as drug treatment targets relevant to the molecular pathology of schizophrenia
DOI: 10.1016/j.phrs.2024.107510
RECENT PROJECTS
2016
Research Grant
A Breakdown of Cortical Homeostasis in Depression: A Focus on the Anterior Cingulate
2011
Research Contracts
Project 4.5 - Novel Therapeutics of Schizophrenia
2011
Research Contracts
Project 4.6 - Biomarkers for Schizophrenia Sub-Types
2015
Research Contracts
Determining the Role of Zip12 in the Pathophysiology Of Schizophrenia