Prof Brian Dean
Honorary (Professorial Fellow)
Department of Psychiatry
480 Scholarly works
16 Projects
HIGHLIGHTS
2025
Journal article
Exon-variant interplay and multi-modal evidence identify endocrine dysregulation in severe psychiatric disorders impacting excitatory neurons
DOI: 10.1038/s41398-025-03366-82025
Journal article
Changes in the Blood Transcriptome Highlights Disturbed Peripheral Biochemical Homeostasis in Bipolar Disorder
DOI: 10.1111/bdi.700582025
Conference Proceedings
591. Muscarinic receptors and the molecular pathology of schizophrenia
DOI: 10.1093/ijnp/pyaf052.3792025
Conference Proceedings
249. Elevated levels of akt-interacting protein in the frontal pole reveals molecular pathology specific to a subtype of people with schizophrenia
DOI: 10.1093/ijnp/pyaf052.0332025
Journal article
Glutamate concentrations and cognitive deficits in ultra-treatment-resistant schizophrenia: An exploratory and comparative 1H-MRS study
DOI: 10.1016/j.pscychresns.2024.1119262024
Journal article
Lower levels of kainate receptors, but not AMPA or NMDA receptors, in Brodmann's area (BA) 9, but not BA 10, from a subgroup of people with schizophrenia who have a marked deficit in cortical muscarinic M1 receptors
DOI: 10.1016/j.schres.2024.09.0142018
Internal Research Grant
Characterising the Muscarinic Receptor Deficit in Schizophrenia
RECENT SCHOLARLY WORKS
2024
Journal article
IUPHAR Review on muscarinic M1 and M4 receptors as drug treatment targets relevant to the molecular pathology of schizophrenia
DOI: 10.1016/j.phrs.2024.1075102024
Journal article
The distribution of Hypocretin/Orexin receptor mRNA in the mouse and human brain
DOI: 10.1016/j.medidd.2024.1002022024
Journal article
Higher levels of AKT-interacting protein in the frontal pole from people with schizophrenia are limited to a sub-group who have a marked deficit in cortical muscarinic M1 receptors
DOI: 10.1016/j.psychres.2024.1161562024
Journal article
Glutamatergic neurotransmission in schizophrenia: A systematic review and quantitative synthesis of proton magnetic resonance spectroscopy studies across schizophrenia spectrum disorders
DOI: 10.1177/00048674241254216
RECENT PROJECTS
2016
Research Grant
A Breakdown of Cortical Homeostasis in Depression: A Focus on the Anterior Cingulate
2011
Research Contracts
Project 4.5 - Novel Therapeutics of Schizophrenia
2011
Research Contracts
Project 4.6 - Biomarkers for Schizophrenia Sub-Types
2015
Research Contracts
Determining the Role of Zip12 in the Pathophysiology Of Schizophrenia