Dr Mohamed Fareh
Honorary Conjoint Senior Fellow
The Sir Peter MacCallum Department of Oncology
24 Scholarly works
1 Projects
HIGHLIGHTS
2026
Journal article
De novo design of potent CRISPR–Cas13 inhibitors
DOI: 10.1038/s41589-025-02136-32025
Journal article
Systematic evaluation of CrRNA design parameters for optimized Cas13d-mediated RNA targeting in chicken cells
DOI: 10.1007/s10142-025-01776-x2025
Research grants (international)
Direct and Indirect Targeting of HIV Tat for Selective RNA Degradation and Protein Suppression
2025
Journal article
Efficient mRNA delivery to resting T cells to reverse HIV latency
DOI: 10.1038/s41467-025-60001-22024
Journal article
Principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision
DOI: 10.1126/sciadv.adl07312024
Journal article
Single-base tiled screen unveils design principles of PspCas13b for potent and off-target-free RNA silencing
DOI: 10.1038/s41594-024-01336-02024
Journal article
CRISPR-Cas13b-mediated suppression of HBV replication and protein expression
DOI: 10.1016/j.jhep.2024.05.025
RECENT SCHOLARLY WORKS
2024
Conference Proceedings
CRISPR-Cas13b-mediated suppression of hepatitis B surface antigen-pre-clinical investigations of a new therapeutic approach
DOI: 10.1016/s0168-8278(24)02081-62024
Journal article
Utilizing CRISPR-Cas13 as a novel functional genomics tool to characterize PAX3-FOXO1 in alveolar rhabdomyosarcoma
DOI: 10.1158/1538-7445.AM2024-10942021
Journal article
Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance
DOI: 10.1038/s41467-021-24577-92021
Journal article
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
DOI: 10.1016/j.molcel.2021.04.015