Dr Ming Shiuan Soh
IT Access
Florey Department of Neuroscience and Mental Health
26 Scholarly works
2 Projects
HIGHLIGHTS
2026
Journal article
Collapse of feed-forward inhibition underpins hyperexcitability in GABAA gain-of-function epilepsy.
DOI: 10.1093/brain/awag1192026
Journal article
The Role of Loss-of-Function KCNH2 Variants in Cardiac Arrhythmias, Seizures and the Risk of Sudden Unexpected Death in Epilepsy
DOI: 10.1111/jnc.704412026
Journal article
Atenolol rescues premature mortality in genetic mouse models of sudden unexpected death in epilepsy
DOI: 10.1111/epi.186422026
Research grants (international)
Determining the Underlying Mechanisms Driving Seizures in PURA Syndrome
2025
Journal article
Org 34167 rescues voltage dependence of mutant channels and normalizes hyperexcitability in HCN1 epilepsy
DOI: 10.1111/epi.185852025
Journal article
BPS2025 - Time-resolved fluorometry reveals novel insights into small molecule drug interactions with the HCN channel voltage sensor
DOI: 10.1016/j.bpj.2024.11.16572022
Research grants (ARC, NHMRC, MRFF)
Treating the Impact of Seizures on Cardiac Function to Reduce Death
RECENT SCHOLARLY WORKS
2025
Journal article
Kv1.1 channels in cardiorespiratory regulation and sudden unexpected death in epilepsy: insights from mouse models
DOI: 10.1093/braincomms/fcaf1162025
Journal article
Development and characterization of a pentylenetetrazol-induced convulsive seizure model in non-anaesthetized sheep
DOI: 10.1093/biomethods/bpaf0862024
Journal article
Different fluorescent labels report distinct components of spHCN channel voltage sensor movement
DOI: 10.1085/jgp.2024135592023
Journal article
The Potential Antidepressant Compound Org 34167 Modulates HCN Channels Via a Novel Mode of Action
DOI: 10.1124/molpharm.123.0006762023
Journal article
Antidepressant-like activity of a brain penetrant HCN channel inhibitor in mice
DOI: 10.3389/fphar.2023.1159527