Dr Sarah Diepstraten
Honorary (Fellow)
Department of Medical Biology (WEHI)
26 Scholarly works
0 Projects
HIGHLIGHTS
2025
Journal article
Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening
DOI: 10.1038/s41467-025-56282-22025
Journal article
MNT: a new target for AML
DOI: 10.1016/j.bneo.2025.1001492025
Journal article
Awakening the Genome: CRISPR Activation to Unravel the Origin and Vulnerabilities of Cancer
DOI: 10.1146/annurev-cancerbio-062624-1041492025
Journal article
Genome-wide in vivo CRISPR screens identify GATOR1 complex as a tumor suppressor in Myc-driven lymphoma
DOI: 10.1038/s41467-025-62615-y2024
Journal article
Don't fear the reaper: The role of regulated cell death in tumorigenesis and BH3-mimetics for cancer therapy
DOI: 10.1016/j.devcel.2024.06.0182024
Journal article
Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
DOI: 10.1016/j.ccell.2024.04.0042021
Journal article
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias
DOI: 10.1182/blood.2020010167
RECENT SCHOLARLY WORKS
2024
Journal article
Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
DOI: 10.1158/2159-8290.CD-23-04022024
Journal article
Genome-wide CRISPR screening identifies a role for ARRDC3 in TRP53-mediated responses
DOI: 10.1038/s41418-023-01249-32023
Journal article
BCL-W makes only minor contributions to MYC-driven lymphoma development
DOI: 10.1038/s41388-023-02804-52023
Book Chapter
Principles for understanding mechanisms of cell death and their role in cancer biology
DOI: 10.1002/9781119819950.ch10