Natasha de Alwis
Postdoctoral Research Fellow
Department of Obstetrics, Gynaecology and Newborn Health
63 Scholarly works
7 Projects
HIGHLIGHTS
2026
Journal article
CRISPR/Cas9-mediated gene editing in trophoblast cells via mechanoporation for preeclampsia insight
DOI: 10.1038/s41419-025-08200-z2026
Journal article
Evaluating valaciclovir, letermovir, and maribavir safety in first-trimester human placental development
DOI: 10.1038/s41598-025-33220-22026
Journal article
Exploring placental dysfunction: models of extracellular vesicle action in preeclampsia
DOI: 10.1093/reprod/xaag0112025
Journal article
Postpartum administration of eplerenone to mitigate vascular dysfunction in mice following a preeclampsia-like pregnancy
DOI: 10.1038/s41598-025-02475-02025
Research grants (other domestic)
Targeting Tumor Necrosis Factor: A Novel Therapeutic Approach to Treat Preeclampsia and Reduce Long-Term Maternal Cardiovascular Disease Risk
2024
Research grants (other domestic)
Tumor Necrosis Factor Inhibition: A New Frontier in Preeclampsia Therapeutics
2023
Research Grant
Selective Endothelin-1 Inhibition: Novel Strategies to Treat Preeclampsia
RECENT SCHOLARLY WORKS
2025
Journal article
Elevated endothelin-1 precedes preeclampsia: does blockade of its receptors have exciting therapeutic potential?
DOI: 10.1016/j.placenta.2025.08.2932025
Journal article
Placental complement component C5 levels are elevated in term preeclampsia - its inhibition does not mitigate placental dysfunction
DOI: 10.1016/j.placenta.2025.08.2972025
Journal article
Correction to: Stem Cell Markers LGR5, LGR4 and Their Immediate Signalling Partners are Dysregulated in Preeclampsia (Stem Cell Reviews and Reports, (2025), 21, 3, (872-896), 10.1007/s12015-024-10831-2)
DOI: 10.1007/s12015-025-10980-y2025
Journal article
Targeted lipid nanoparticle delivery of short interfering RNA to treat preeclampsia
DOI: 10.1016/j.placenta.2025.08.0112025
Journal article
Hypoxia alters the proteome of small human placental extracellular vesicles and their effect on endothelial dysfunction.
DOI: 10.1016/j.placenta.2025.08.0972025
Journal article
Amniotic Fluid Extracellular Vesicle Properties Evolve With Gestational Age and Reflect Fetal Development
DOI: 10.1002/jex2.70085
RECENT PROJECTS
2025
Research grants (other domestic)
AMRF Grant: Enhancing Nanoparticle Delivery of RNA Therapies to the Placenta
2024
Research grants (other domestic)
Development of Placentoids: Next Generation Placenta Models for Drug Discovery