Dr. Elham Khajehali
Research Fellow - Liver Metabolism
Anatomy and Physiology
14 Scholarly works
0 Projects
HIGHLIGHTS
2020
Journal article
Restoring Agonist Function at a Chemogenetically Modified M-1 Muscarinic Acetylcholine Receptor
DOI: 10.1021/acschemneuro.0c005402020
Journal article
Development of Novel 4-Arylpyridin-2-one and 6-Arylpyrimidin-4-one Positive Allosteric Modulators of the M(1)Muscarinic Acetylcholine Receptor
DOI: 10.1002/cmdc.2020005402020
Journal article
Negative allosteric modulators of the human calcium-sensing receptor bind to overlapping and distinct sites within the 7-transmembrane domain
DOI: 10.1111/bph.149612019
Conference Proceedings
The in vitro characterisation of DREADD agonist 21, a novel ligand for muscarinic DREADD receptors
2019
Journal article
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M-1 mAChR: The Determinants of Allosteric Activity
DOI: 10.1021/acschemneuro.8b006132018
Journal article
Dual Action Calcium-Sensing Receptor Modulator Unmasks Novel Mode-Switching Mechanism
DOI: 10.1021/acsptsci.8b000212018
Journal article
DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs in Vitro and in Vivo
DOI: 10.1021/acsptsci.8b00012
RECENT SCHOLARLY WORKS
2018
Journal article
Probing the binding site of novel selective positive allosteric modulators at the M-1 muscarinic acetylcholine receptor
DOI: 10.1016/j.bcp.2018.05.0092018
Journal article
Assessment of the Molecular Mechanisms of Action of Novel 4-Phenylpyridine-2-One and 6-Phenylpyrimidin-4-One Allosteric Modulators at the M-1 Muscarinic Acetylcholine Receptors
DOI: 10.1124/mol.118.1116332018
Journal article
Synthesis and Pharmacological Evaluation of Heterocyclic Carboxamides: Positive Allosteric Modulators of the M-1 Muscarinic Acetylcholine Receptor with Weak Agonist Activity and Diverse Modulatory Profiles
DOI: 10.1021/acs.jmedchem.7b01812