Dr Chris Horne
Honorary (Fellow)
Department of Medical Biology (WEHI)
37 Scholarly works
0 Projects
HIGHLIGHTS
2026
Journal article
The kinase domain of RIPK3 tunes its scaffolding functions
DOI: 10.1038/s41418-026-01677-x2025
Journal article
Mechanism of NanR transcriptional activation of sialic acid metabolism in Streptococcus pneumoniae.
DOI: 10.64898/2025.12.10.6934822025
Journal article
PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2 sensor proteins
DOI: 10.1073/pnas.24209611222025
Journal article
Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activity
DOI: 10.1042/BCJ202534312024
Journal article
Large-scale genomic investigation of pediatric cholestasis reveals a novel hepatorenal ciliopathy caused by PSKH1 mutations
DOI: 10.1016/j.gim.2024.1012312024
Journal article
An immunohistochemical atlas of necroptotic pathway expression
DOI: 10.1038/s44321-024-00074-62024
Journal article
TRAPs: the 'elevator-with-an-operator' mechanism
DOI: 10.1016/j.tibs.2023.11.006
RECENT SCHOLARLY WORKS
2024
Journal article
Inhibitors identify an auxiliary role for mTOR signalling in necroptosis execution downstream of MLKL activation
DOI: 10.1042/BCJ202402552023
Journal article
A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation
DOI: 10.1038/s41467-023-41724-62023
Journal article
Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization
DOI: 10.1038/s41467-023-42255-w