Dr. Chris Horne
Honorary
Medical Biology (w.e.h.i.)
16 Scholarly works
0 Projects
HIGHLIGHTS
2021
Journal article
N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization
DOI: 10.1016/j.jbc.2021.1011132021
Journal article
SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization
DOI: 10.1042/BCJ202102782021
Journal article
Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL
DOI: 10.1101/2021.05.03.4423852021
Journal article
Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis
DOI: 10.1038/s41467-021-22400-z2021
Journal article
Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
DOI: 10.1038/s41467-021-22253-62021
Journal article
For Whom the Bell Tolls: The Structure of the Dead Kinase, IRAK3
DOI: 10.1016/j.str.2021.01.0112021
Journal article
A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells
DOI: 10.1038/s41418-021-00742-x
RECENT SCHOLARLY WORKS
2021
Journal article
Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory alpha C helix
DOI: 10.1038/s41467-021-21191-72021
Journal article
Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2
DOI: 10.1016/j.jbc.2021.1004942020
Journal article
Multi-wavelength analytical ultracentrifugation as a tool to characterise protein-DNA interactions in solution
DOI: 10.1007/s00249-020-01481-6