A/Prof Shabih Shakeel
Principal Research Fellow
Department of Biochemistry and Pharmacology
24 Scholarly works
1 Projects
HIGHLIGHTS
2026
Journal article
Embryonic stem cell factors DPPA2/4 amplify active H3K4me3-H2AK119ub chromatin domains in non-small cell lung cancer.
DOI: 10.1101/gad.353102.1252025
Journal article
MORC2 is a phosphorylation-dependent DNA compaction machine
DOI: 10.1038/s41467-025-60751-z2025
Research grants (ARC, NHMRC, MRFF)
How Cells Perform Error-Free Repair of Damaged DNA?
2025
Journal article
Cryo-EM structure of endogenous Plasmodium falciparum Pfs230 and Pfs48/45 fertilization complex
DOI: 10.1126/science.ady02412025
Journal article
Structural basis of Fanconi anemia pathway activation by FANCM
DOI: 10.1038/s44318-025-00468-32025
Conference Proceedings
From Atomic Interactions to Cellular Dynamics: Multiscale Insights into MORC2 Function
DOI: 10.14293/apmc13-2025-03532023
Journal article
Mechanism of autoinhibition and activation of the human MORC2 GHKL ATPase
DOI: 10.1107/s2053273323087545
RECENT SCHOLARLY WORKS
2022
Journal article
The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination
DOI: 10.1038/s41594-022-00820-92020
Journal article
Structure of Nora virus at 2.7 Å resolution and implications for receptor binding, capsid stability and taxonomy
DOI: 10.1038/s41598-020-76613-12020
Journal article
FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair
DOI: 10.1038/s41594-020-0380-12020
Journal article
Deep learning enables the atomic structure determination of the Fanconi Anemia core complex from cryoEM
DOI: 10.1107/S2052252520009306