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Email

lewis.a2@unimelb.edu.au

Credentials


Position
Honorary Conjoint Fellow
The Sir Peter MacCallum Department of Oncology

Dr Alexander Lewis

Honorary Conjoint Fellow
The Sir Peter MacCallum Department of Oncology

8 Scholarly works
0 Projects

HIGHLIGHTS

  • 2026

    Journal article

    Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia
    DOI: 10.1016/j.cell.2025.10.028
  • 2022

    Journal article

    Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells
    DOI: 10.1016/j.celrep.2022.111182
  • 2022

    Journal article

    Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma
    DOI: 10.1038/s41375-022-01571-8
  • 2020

    Journal article

    ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism
    DOI: 10.1038/s41556-020-0523-y
  • 2019

    Journal article

    Identification of sphingosine kinase 1 as a therapeutic target in B-lineage acute lymphoblastic leukaemia
    DOI: 10.1111/bjh.15097
  • 2019

    Journal article

    Kelch-like protein 5-mediated ubiquitination of lysine 183 promotes proteasomal degradation of sphingosine kinase 1
    DOI: 10.1042/BCJ20190245
  • 2018

    Journal article

    Targeting sphingolipid metabolism as an approach for combination therapies in haematological malignancies
    DOI: 10.1038/s41420-018-0075-0
Alexander Lewis

RECENT SCHOLARLY WORKS

  • 2017

    Journal article

    The MCL-1 inhibitor S63845: an exciting new addition to the armoury of anti-cancer agents
    DOI: 10.21037/jxym.2017.05.07

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