Dr. Leonie Quinn
Honorary
Anatomy and Physiology
49 Scholarly works
10 Projects
HIGHLIGHTS
2015
Journal article
Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models
DOI: 10.1038/ncomms84042015
Journal article
Targeting RNA polymerase I to treat MYC-driven cancer
DOI: 10.1038/onc.2014.132014
Research Grant
USING GENETIC MODELS TO ELUCIDATE NOVEL MECHANISMS CONTROLLING CELL GROWTH
2012
Research Grant
Deciphering the cellular defenses against aggregating proteins in human disease
2011
Journal article
Drosophila Ribosomal Protein Mutants Control Tissue Growth Non-Autonomously via Effects on the Prothoracic Gland and Ecdysone
DOI: 10.1371/journal.pgen.10024082010
Journal article
Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner
DOI: 10.1242/dev.0495852004
Journal article
Drosophila Hfp negatively regulates dmyc and stg to inhibit cell proliferation
DOI: 10.1242/dev.01019
RECENT SCHOLARLY WORKS
2020
Journal article
MYC in Brain Development and Cancer.
DOI: 10.3390/ijms212077422020
Journal article
Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study
DOI: 10.1016/S1474-4422(20)30273-82020
Journal article
Elevated levels of Drosophila Wdr62 promote glial cell growth and proliferation through AURKA signalling to AKT and MYC.
DOI: 10.1016/j.bbamcr.2020.1187132020
Journal article
Transcriptional repression of Myc underlies the tumour suppressor function of AGO1 in Drosophila
DOI: 10.1242/dev.1902312018
Journal article
The Role of WD40-Repeat Protein 62 (MCPH2) in Brain Growth: Diverse Molecular and Cellular Mechanisms Required for Cortical Development
DOI: 10.1007/s12035-017-0778-x2018
Journal article
DNA Conformation Regulates Gene Expression: The MYC Promoter and Beyond
DOI: 10.1002/bies.2017002352017
Journal article
A Kinome RNAi Screen in Drosophila Identifies Novel Genes Interacting with Lgl, aPKC, and Crb Cell Polarity Genes in Epithelial Tissues
DOI: 10.1534/g3.117.0435132017
Journal article
Glial-Specific Functions of Microcephaly Protein WDR62 and Interaction with the Mitotic Kinase AURKA Are Essential for Drosophila Brain Growth
DOI: 10.1016/j.stemcr.2017.05.015