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Email

pcrack@unimelb.edu.au

Credentials


Position
Professor
Department of Biochemistry and Pharmacology
Education
PhD
Monash University
Bachelors Degree (Honours)
Monash University
Graduate Certificate
University of Melbourne
ORCID

0000-0002-5030-0330

Prof Peter Crack

Professor
Department of Biochemistry and Pharmacology

120 Scholarly works
36 Projects

HIGHLIGHTS

  • 2026

    Journal article

    Type I Interferons Drive the Gastrointestinal Inflammatory Response in a Mouse Model of Parkinson’s Disease
    DOI: 10.1016/j.gastha.2026.100929
  • 2025

    Journal article

    The contribution of type-I IFN-mediated neuroinflammation to Parkinson's disease progression
    DOI: 10.1016/j.bbih.2025.101017
  • 2025

    Journal article

    Generative AI and digital twins: shaping a paradigm shift from precision to truly personalized medicine
    DOI: 10.1080/17460441.2025.2507376
  • 2025

    Thesis / Dissertation

    Characterisation of the role of the type-I Interferons in the alpha-synuclein model of Parkinson's disease
  • 2023

    Research grants (other domestic)

    Discovery of STING Inhibitors for the Treatment of MND
  • 2019

    Research Grant

    Utilising Biomaterials to Harness Endogenous Neural Stem Cells for Brain Repair
  • 2018

    Research Grant

    Understanding Neuroinflammation in Alzheimer's Disease
Peter Crack

RECENT SCHOLARLY WORKS

  • 2024

    Journal article

    IKKɛ induces STING non-IFN immune responses via a mechanism analogous to TBK1
    DOI: 10.1016/j.isci.2024.110693
  • 2024

    Journal article

    Pharmacological inhibition of STING reduces neuroinflammation-mediated damage post-traumatic brain injury
    DOI: 10.1111/bph.16347
  • 2023

    Journal article

    ALTERATION OF NEUROIMMUNE PATHWAYS RESCUES IMPAIRED INTESTINAL PERMEABILITY AND BEHAVIOUR IN A MOUSE MODEL OF COLITIS
    DOI: 10.1016/j.ibneur.2023.08.495
  • 2023

    Conference Proceedings

    iBalls: an updated and expanded iris simulator for teaching autonomic pharmacology and the utility of drugs in an ocular diagnostic setting
  • 2022

    Book Chapter

    The Emerging Role of the Gut-Brain-Microbiota Axis in Neurodevelopmental Disorders.
    DOI: 10.1007/978-3-031-05843-1_14
  • 2021

    Journal article

    Biomaterial Strategies for Restorative Therapies in Parkinson's Disease
    DOI: 10.1021/acschemneuro.1c00484
  • 2021

    Journal article

    The Complexity of the cGAS-STING Pathway in CNS Pathologies
    DOI: 10.3389/fnins.2021.621501

RECENT PROJECTS

  • 2026

    Research grants (ARC, NHMRC, MRFF)

    Targeting STING in Treating Traumatic Brain Injury.

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