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Email

hamish.mcwilliam@unimelb.edu.au

Credentials


Position
Honorary (Senior Fellow)
Department of Microbiology and Immunology
Education
PhD
Monash University
Bachelors Degree (Honours)
Deakin University
ORCID

0000-0003-3479-3419

Dr Hamish McWilliam

Honorary (Senior Fellow)
Department of Microbiology and Immunology

64 Scholarly works
7 Projects

HIGHLIGHTS

  • 2026

    Journal article

    Allelic variation alters expression and antigen presentation of MR1 allomorphs
    DOI: 10.1016/j.jbc.2026.111470
  • 2026

    Journal article

    The antigen-presenting molecule MR1 binds host-generated riboflavin catabolites
    DOI: 10.1084/jem.20250711
  • 2026

    Journal article

    Macrophage MR1 antigen presentation promotes MAIT cell immunity and lung microbiota modulation
    DOI: 10.1126/science.adr6322
  • 2026

    Book Chapter

    MR1 and MAIT Cells
    DOI: 10.1016/b978-0-128-24465-4.00120-4
  • 2021

    Research grants (ARC, NHMRC, MRFF)

    Presentation of Metabolite Antigens by MR1 Molecules: A Fundamental System of Immune Priming
  • 2018

    Research Grant

    The CASS Foundation Medicine Science Grant 2017
  • 2017

    Research Grant

    Defining a Novel Mechanism of Pathogen Detection Conserved in Mammals
Hamish McWilliam

RECENT SCHOLARLY WORKS

  • 2025

    Book Chapter

    MR1 and MAIT Cells
    DOI: 10.1016/B978-0-128-24465-4.00120-4
  • 2024

    Journal article

    Prior infection with unrelated neurotropic virus exacerbates influenza disease and impairs lung T cell responses
    DOI: 10.1038/s41467-024-46822-7
  • 2024

    Journal article

    Correction to: Sepsis-trained macrophages promote antitumoral tissue-resident T cells (Nature Immunology, (2024), 25, 5, (802-819), 10.1038/s41590-024-01819-8)
    DOI: 10.1038/s41590-024-02000-x
  • 2024

    Journal article

    Impaired endocytosis and accumulation in early endosomal compartments defines herpes simplex virus–mediated disruption of the nonclassical MHC class I–related molecule MR1
    DOI: 10.1016/j.jbc.2024.107748
  • 2024

    Journal article

    Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis
    DOI: 10.1002/ange.202400632
  • 2024

    Journal article

    Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis
    DOI: 10.1002/anie.202400632

RECENT PROJECTS

  • 2020

    Research Contracts

    Creating a Genetically Modified Mouse Line, MR1-K43A
  • 2017

    Internal Research Grant

    Defining a Novel Mechanism of Pathogen Detection Conserved in Mammals

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