Modulation Of Feeding Through Pharmacological Targeting Of The Relaxin-3 Receptor Rxfp3

Grant number: 1066369 | Funding period: 2014 - 2016

Completed

Abstract

Relaxin-3 is a neuropeptide that regulates a number of physiological processes, including food intake, suggesting that the relaxin-3 receptor RXFP3 may be a new target for treatment of eating disorders such as obesity. This project will develop new selective and high-affinity ligands for RXFP3, which will be critical pharmacological tools for the preclinical studies and evaluation of this system.