A COMBINED PET-FMRI STUDY OF FRONTOSTRIATAL DYSFUNCTION IN FIRST EPISODE PSYCHOSIS

Grant number: 1066779 | Funding period: 2014 - 2019

Completed

Abstract

Psychosis is a debilitating psychiatric syndrome affecting a person’s ability to understand reality. This project will map how disruptions of specific brain circuits give rise to psychosis, and how they relate to changes in the level of a specific brain chemical, dopamine, which is targeted by antipsychotic medications. This work has important implications for developing new, more targeted treatments.