CELLULAR AND MOLECULAR MECHANISMS OF FUNGAL INFECTION PATHOGENESIS AND THERAPY

Grant number: 1069284 | Funding period: 2014 - 2016

Completed

Abstract

Fungal infections are serious problems for patients with depressed immunity such as chemotherapy or transplant patients. More effective antifungal treatments are needed. We will study a model of fungal infection in zebrafish embryos that recapitulates human penicilliosis. The research will study how the infection establishes and how different types of white blood cells either help or hinder infection establishment. The results will point to new approaches for treating serious fungal infections.

University of Melbourne Researchers