The Genetics of Adhd: Role of Rare Variants

Grant number: 1065677 | Funding period: 2014 - 2016

Completed

Abstract

Attention deficit hyperactivity disorde(ADHD) is the most prevalent mental disorder of childhood affecting around 7.5% of Australian school age children. The disorder is strongly genetic and causes significant impairments in academic functioning, family and peer relations with sufferers at increased risk for drug abuse. Identification and characterisation of rare mutations will enhance our knowledge of the neurobiology and advance the search for next generation drug treatments for the disorder.

Related publications (2)

A case–control genome-wide association study of ADHD discovers a novel association with the tenascin R (TNR) gene

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2018-12-01

It is well-established that there is a strong genetic contribution to the aetiology of attention deficit hyperactivity disorder (A..

Separating the wheat from the chaff: Systematic identification of functionally relevant noncoding variants in ADHD

JHS Tong, Z Hawi, C Dark, TDR Cummins, BP Johnson, DP Newman, R Lau, A Vance, HS Heussler, N Matthews, MA Bellgrove, KC Pang

2016-11-01

Attention deficit hyperactivity disorder (ADHD) is a highly heritable psychiatric condition with negative lifetime outcomes. Uncov..

University of Melbourne Researchers

Alasdair Vance