THE IMPACT OF HIV INTEGRATION SITES ON ELIMINATING HIV LATENCY

Grant number: 1058891 | Funding period: 2014 - 2016

Completed

Abstract

Current antiviral therapy for HIV controls virus production and allows recovery but does not eliminate the silent infection that prevents complete virus elimination and cure. We will examine two ways that HIV can silently infect T cells for differences in the sites at which the HIV DNA inserts into the genome. We will examine the way in which these differences at the genomic level may limit the ability to activate and eliminate persistent infection in memory T cells.

Related publications (4)

University of Melbourne Researchers