CELL INTERACTIONS PRODUCING HIV LATENCY

Grant number: 1041795 | Funding period: 2014 - 2015

Completed

Abstract

Current anti-HIV therapies can't cure HIV because HIV remains silent(latent) in long-lived cells. The HIV life cycle and virus production is linked to activation of the host cell, which is regulated by dendritic cells. This grant will explore how the factors controlling T cell activation and proliferation control virus expression and latency. By understanding how latent infection is established and maintained, these studies will potentially identify new ways to eliminate HIV infection.

University of Melbourne Researchers