What Helps Hiv Hide in the Body?

Abstract

Current drug treatments can not eradicate HIV from the body. This is because HIV can infect and establish a latent or “silent” infection in long-lived cells of the immune system that can re-emerge out of these cells when drug treatment is stopped. This project aims to find out how these cells become infected and what type of HIV is infecting them. The results from this study will help us better understand the latent infection and will help researchers design ways to eradicate HIV.

Related publications (1)

Longitudinal analysis of subtype C envelope tropism for memory CD4 T cell subsets over the first 3 years of untreated HIV-1 infection

MJ Gartner, PR Gorry, C Tumpach, J Zhou, A Dantanarayana, JJ Chang, TA Angelovich, P Ellenberg, AE Laumaea, M Nonyane, PL Moore, SR Lewin, MJ Churchill, JK Flynn, M Roche

2020-08-06

Background: HIV-1 infects a wide range of CD4+ T cells with different phenotypic properties and differing expression levels of ent..