Arc Centre of Excellence in Convergent Bio–nano Science and Technology

Super-resolution Imaging of Proton Sponge-Triggered Rupture of Endosomes and Cytosolic Release of Small Interfering RNA

M Wojnilowicz, A Glab, A Bertucci, F Caruso, F Cavalieri

2019-01-22

The intracellular delivery of nucleic acids and proteins remains a key challenge in the development of biological therapeutics. In..

In Situ Characterization of Protein Corona Formation on Silica Microparticles Using Confocal Laser Scanning Microscopy Combined with Microfluidics

ACG Weiss, K Krüger, QA Besford, M Schlenk, K Kempe, S Förster, F Caruso

2019-01-16

In biological fluids, proteins bind to particles, forming so-called protein coronas. Such adsorbed protein layers significantly in..

Supramolecular Metal–Phenolic Gels for the Crystallization of Active Pharmaceutical Ingredients

MA Rahim, Y Hata, M Björnmalm, Y Ju, F Caruso

2018-06-27

The use of supramolecular gel media for the crystallization of active pharmaceutical ingredients (APIs) is of interest for control..

The complexities and caveats of lineage tracing in the mammary gland

AC Rios, NY Fu, J Cursons, GJ Lindeman, JE Visvader

2016-11-25

Lineage tracing is increasingly being utilised to probe different cell types that exist within the mammary gland. Whilst this tech..

Differential responses of pattern recognition receptors to outer membrane vesicles of three periodontal pathogens

JD Cecil, NM O'Brien-Simpson, JC Lenzo, JA Holden, YY Chen, W Singleton, KT Gause, Y Yan, F Caruso, EC Reynolds

2016-04-01

Highly purified outer membrane vesicles (OMVs) of the periodontal pathogens, Porphyromonas gingivalis, Treponema denticola and Tan..