CONTROL OF ORGAN SIZE AND CANCER BY THE HIPPO PATHWAY

Grant number: 1078220 | Funding period: 2015 - 2020

Completed

Abstract

The Hippo pathway is a key regulator of tissue growth. It was first discovered in vinegar flies and plays a similar role in mammals. We aim to define the mechanism by which the Hippo pathway controls tissue growth and cancer. These studies will be performed in flies and mammalian cell culture. Our studies will shed light on how tissue growth is controlled, and have the potential to inform the way that we treat human cancers and tissue growth disorders.

Related publications (15)

University of Melbourne Researchers