RECOGNITION OF LIPID ANTIGENS BY CD1D-RESTRICTED TYPE-2 NKT CELLS

Grant number: 1083885 | Funding period: 2015 - 2017

Completed

Abstract

Protection against infection depends on T cells, which recognise and target foreign molecules called antigens via a specialized antigen receptor known as a T cell receptor (TCR). This project focuses on a specialised population of T cells called Natural Killer T (NKT) cells that recognise lipid antigens. The work outlined in this grant will increase our understanding of how different TCRs can recognise diverse lipid antigens thus providing insight into the role of NKT cells in the immune system.

University of Melbourne Researchers