CHROMATIN DYNAMICS DURING SEXUAL DIFFERENTIATION IN THE MALARIA PARASITE P. FALCIPARUM

Grant number: 1084580 | Funding period: 2015 - 2018

Completed

Abstract

Inhibiting malaria transmission is a critical step towards global eradication of this deadly disease. This proposal aims to understand the mechanisms regulating the expression of genes which control the differentiation of the transmission stages of malaria parasites. Such pathways are prime targets for novel anti-malarial drugs.

Related publications (1)

The Putative Bromodomain Protein PfBDP7 of the Human Malaria Parasite Plasmodium Falciparum Cooperates With PfBDP1 in the Silencing of Variant Surface Antigen Expression

Jennifer E Quinn, Myriam D Jeninga, Katharina Limm, Kapil Pareek, Tina Meissgeier, Anna Bachmann, Michael F Duffy, Michaela Petter

2022-04-12

Epigenetic regulation is a critical mechanism in controlling virulence, differentiation, and survival of the human malaria parasit..

University of Melbourne Researchers

Michaela Petter Microbiology and Immunology