CHROMATIN DYNAMICS DURING SEXUAL DIFFERENTIATION IN THE MALARIA PARASITE P. FALCIPARUM
Grant number: 1084580 | Funding period: 2015 - 2018
Inhibiting malaria transmission is a critical step towards global eradication of this deadly disease. This proposal aims to understand the mechanisms regulating the expression of genes which control the differentiation of the transmission stages of malaria parasites. Such pathways are prime targets for novel anti-malarial drugs.
Related publications (1)
The Putative Bromodomain Protein PfBDP7 of the Human Malaria Parasite Plasmodium Falciparum Cooperates With PfBDP1 in the Silencing of Variant Surface Antigen Expression
Jennifer E Quinn, Myriam D Jeninga, Katharina Limm, Kapil Pareek, Tina Meissgeier, Anna Bachmann, Michael F Duffy, Michaela Petter
Epigenetic regulation is a critical mechanism in controlling virulence, differentiation, and survival of the human malaria parasit..