THE FUNCTIONAL INTERPLAY BETWEEN ALPHA SYNUCLEIN AND SYNAPTOPHYSIN IN SYNAPTIC VESICLE RECYCLING

Grant number: 1085483 | Funding period: 2015 - 2019

Completed

Abstract

Parkinson’s Disease (PD) is the second most common neurodegenerative disorder, affecting 7 million people worldwide. α-synuclein is a protein in that brain that is likely to contribute to the death of brain cells in PD, but the normal role of the protein remains unknown. This study will investigate the function of α-synuclein in maintaining normal healthy brain activity. In addition, this work will help us understand the processes that go awry in neurodegenerative disease states such as PD.

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