CHARACTERISATION OF PORPHYROMONAS GINGIVALIS AND TREPONEMA DENTICOLA INTERACTIONS IN THE DEVELOPMENT OF A PATHOGENIC BIOFILM
Grant number: 1083600 | Funding period: 2015 - 2017
Gum disease (periodontitis) is an inflammatory disease caused by bacterial pathogens that is the major cause of tooth loss in adults. It is also associated with systemic diseases such as cardiovascular disease. In this study we will determine the mechanisms by which two bacterial species work together to produce the pathogenic dental plaque that causes disease.
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Metabolic cooperativity betweenPorphyromonas gingivalisandTreponema denticola
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Background: Porphyromonas gingivalis and Treponema denticola are proteolytic periodontopathogens that co-localize in polymicrobia..
The Role of Treponema denticola Motility in Synergistic Biofilm Formation With Porphyromonas gingivalis
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Chronic periodontitis has a polymicrobial biofilm etiology and interactions between key oral bacterial species, such as Porphyromo..
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PgMntR is a predicted member of the DtxR family of transcriptional repressors responsive to manganese in the anaerobic periodontal..
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Tannerella forsythia, a Gram-negative oral bacterium closely associated with chronic periodontitis, naturally produces outer membr..
Lysine acetylation is a common post-translational modification of key metabolic pathway enzymes of the anaerobe Porphyromonas gingivalis
Catherine A Butler, Paul D Veith, Matthew F Nieto, Stuart G Dashper, Eric C Reynolds
Porphyromonas gingivalis is a Gram-negative anaerobe considered to be a keystone pathogen in the development of the bacterial-asso..